ADH6 Antikörper (AA 11-110) (HRP)

Produktnummer ABIN1712480

Der Kaninchen Polyklonal Anti-ADH6-Antikörper wurde für ELISA, IHC (p) und IHC (fro) validiert. Er ist geeignet, ADH6 in Proben von Human zu detektieren.

Kurzübersicht für ADH6 Antikörper (AA 11-110) (HRP) (ABIN1712480)

Target: ADH6 (Alcohol Dehydrogenase 6 (Class V) (ADH6))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ADH6 Antikörper ist konjugiert mit HRP

Applikation: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-ADH6 Antikörper (HRP)

Bindungsspezifität: AA 11-110

Homologie: Human,Mouse,Rat,Cow,Pig

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ADH6

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handhabung: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu ADH6

Target: ADH6 (Alcohol Dehydrogenase 6 (Class V) (ADH6))

Andere Bezeichnung: ADH6

Hintergrund:

Synonyms: ADH 5, ADH 6, Adh6, ADH6_HUMAN, Alcohol dehydrogenase 6 class V, Alcohol dehydrogenase 6, Aldehyde reductase, Class V alcohol dehydrogenase 6, UDP GLUCURONOSYLTRANSFERASE 2B10 PRECURSOR, MICROSOMAL.

Background: ADH6 (alcohol dehydrogenase 6), also known as ADH-5, is a 368 amino acid member of the class V zinc-containing alcohol dehydrogenase family. This family of enzymes functions to metabolize a wide variety of substrates such as retinol, hydroxysteroids, ethanol, aliphatic alcohols and lipid peroxidation products. Localized to the cytoplasm and expressed in the stomach and liver, ADH6 catalyzes the reversible oxidation of alcohols to their corresponding aldehydes or ketones and is able to bind two zinc ions as cofactors. ADH6 contains a glucocorticoid response element upstream of its 5' UTR which is thought to be a steroid binding site, suggesting that expression of ADH6 may be under hormonal control. Multiple isoforms of ADH6 exist due to alternative splicing events.

Gen-ID: 130