ZAK Antikörper (AA 1-100) (HRP)
-
- Target Alle ZAK Antikörper anzeigen
- ZAK (Mitogen-Activated Protein Kinase Kinase Kinase MLT (ZAK))
-
Bindungsspezifität
- AA 1-100
-
Reaktivität
- Maus, Ratte
-
Wirt
- Kaninchen
-
Klonalität
- Polyklonal
-
Konjugat
- Dieser ZAK Antikörper ist konjugiert mit HRP
-
Applikation
- ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Kreuzreaktivität
- Maus, Ratte
- Homologie
- Human,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human ZAK/HCCS4
- Isotyp
- IgG
- Top Product
- Discover our top product ZAK Primärantikörper
-
-
- Applikationshinweise
-
IHC-P 1:200-400
IHC-F 1:100-500 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Handhabung
- Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Haltbarkeit
- 12 months
-
- Target
- ZAK (Mitogen-Activated Protein Kinase Kinase Kinase MLT (ZAK))
- Andere Bezeichnung
- ZAK/HCCS4 (ZAK Produkte)
- Synonyme
- MLTK antikoerper, RGD1561394 antikoerper, AZK antikoerper, MLK7 antikoerper, MLT antikoerper, MRK antikoerper, mlklak antikoerper, pk antikoerper, AV006891 antikoerper, B230120H23Rik antikoerper, MLTKalpha antikoerper, MLTKbeta antikoerper, mitogen-activated protein kinase kinase kinase 20 antikoerper, Map3k20 antikoerper, MAP3K20 antikoerper
- Hintergrund
-
Synonyms: AZK, Cervical cancer suppressor gene 4 protein, HCCS 4, HCCS-4, HCCS4, Human cervical cancer suppressor gene 4 protein, Leucine zipper and sterile alpha mot containing kinase, Leucine zipper- and sterile alpha mot-containing kinase, Mitogen activated protein kinase kinase kinase MLT, Mitogen-activated protein kinase kinase kinase MLT, Mixed lineage kinase 7, Mixed lineage kinase related kinase, Mixed lineage kinase related kinase MRK beta, Mixed lineage kinase with a leucine zipper and a sterile alpha mot, Mixed lineage kinase-related kinase, MLK 7, MLK like mitogen activated protein triple kinase, MLK related kinase, MLK-like mitogen-activated protein triple kinase, MLK-related kinase, MLK7, Mlklak, MLT, MLTK, MLTK_HUMAN, MRK, Sterile alpha mot and leucine zipper containing kinase AZK, Sterile alpha mot- and leucine zipper-containing kinase AZK, ZAK.
Background: Stress-activated component of a protein kinase signal transduction cascade. Regulates the JNK and p38 pathways. Pro-apoptotic. Role in regulation of S and G2 cell cycle checkpoint by direct phosphorylation of CHEK2. Isoform 1, but not isoform 2, causes cell shrinkage and disruption of actin stress fibers. Isoform 1 may have role in neoplastic cell transformation and cancer development. Isoform 1, but not isoform 2, phosphorylates histone H3 at 'Ser-28'.
- Gen-ID
- 51776
-