BTBD14A Antikörper (AA 401-500) (HRP)

Produktnummer ABIN1711556

Der Kaninchen Polyklonal Anti-BTBD14A-Antikörper wurde für ELISA, IHC (p) und IHC (fro) validiert. Er ist geeignet, BTBD14A in Proben von Human zu detektieren.

Kurzübersicht für BTBD14A Antikörper (AA 401-500) (HRP) (ABIN1711556)

Target: BTBD14A (BTB (POZ) Domain Containing 14A (BTBD14A))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BTBD14A Antikörper ist konjugiert mit HRP

Applikation: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-BTBD14A Antikörper (HRP)

Bindungsspezifität: AA 401-500

Homologie: Human,Mouse,Rat,Dog,Cow,Sheep,Horse,Chicken

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human BTBD14A

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handhabung: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu BTBD14A

Target: BTBD14A (BTB (POZ) Domain Containing 14A (BTBD14A))

Andere Bezeichnung: BTBD14A

Hintergrund:

Synonyms: BTB POZ domain containing 14A, BTB domain containing 14A, BTB/POZ domain containing protein 14A, BTB/POZ domain-containing protein 14A, BTBD 14A, BTBD14, NAC-2, NACC2, NACC2_HUMAN, Nucleus accumbens-associated protein 2.

Background: BTBD14A is a 587 amino acid protein that contains one BTB/POZ domain. The BTB/POZ domain mediates homomeric and heteromeric POZ-POZ interactions and is common to transcriptional regulators involved in chromatin modeling. In several BTB/POZ containing proteins, including BCL-6 and the promyelocytic leukemia zinc-finger (PLZF) oncoprotein, this domain interacts with the SMRT/N-CoR-mSin3A HDAC complex and is directly involved in repressing and silencing gene transcription. When this domain is deleted, as with the oncogenic PLZF-RAR chimera of promyelocytic leukemias, this transcriptional repression is attenuated. This suggests that BTBD14A may play a role in transcription regulation.

Gen-ID: 54813

Pathways: Positive Regulation of Response to DNA Damage Stimulus