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FN3K Antikörper (AA 201-309) (HRP)

This anti-FN3K antibody (ABIN1711302) is a Rabbit Polyclonal antibody detecting FN3K in WB, ELISA, IHC (p), IHC (fro). Suitable for Human.
Produktnummer ABIN1711302

Quick Overview for FN3K Antikörper (AA 201-309) (HRP) (ABIN1711302)

Target

Alle FN3K Antikörper anzeigen
FN3K (Fructosamine 3 Kinase (FN3K))

Reaktivität

  • 31
  • 4
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  • 1
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Human

Wirt

  • 26
  • 5
Kaninchen

Klonalität

  • 26
  • 5
Polyklonal

Konjugat

  • 16
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Dieser FN3K Antikörper ist konjugiert mit HRP

Applikation

  • 31
  • 13
  • 13
  • 8
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  • 6
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  • 2
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Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • Bindungsspezifität

    • 14
    • 4
    • 1
    • 1
    • 1
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    AA 201-309

    Homologie

    Human,Mouse,Rat

    Aufreinigung

    Purified by Protein A.

    Immunogen

    KLH conjugated synthetic peptide derived from human FN3K

    Isotyp

    IgG
  • Applikationshinweise

    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 μg/μL

    Buffer

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    Konservierungsmittel

    ProClin

    Vorsichtsmaßnahmen

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Handhabung

    Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    Haltbarkeit

    12 months
  • Target

    FN3K (Fructosamine 3 Kinase (FN3K))

    Andere Bezeichnung

    FN3K

    Hintergrund

    Synonyms: 2310074G21Rik, Fnsk, Fructosamine 3 kinase, RP23-293H17.4, FN3K_HUMAN.

    Background: Amines, including those present on proteins, spontaneously react with glucose to make fructosamines in a reaction termed glycation. Fructosamine 3-kinase (FN3K), a 309-amino acid enzyme initially identified in erythrocytes, catalyzes the ATP-dependent phosphorylation of the third carbon on both D- and L-fructosamines, leading to their destabilization and eventually, their removal from the protein. FN3K is a monomer that is ubiquitously expressed in mammalian tissue and phosphorylates both low molecular mass and protein-bound fructosamines which are formed as a result of glycation of glucose with primary amines. FN3K protects proteins from the harmful effects of nonenzymatic glycation, and may also be involved in peptide repair and cell metabolism. FN3KRP (fructosamine-3-kinase-related protein) is a 309 amino acid protein that is expressed in erythrocytes, bone marrow, spleen, brain and kidney and belongs to the fructosamine kinase family. FN3KRP functions to phosphorylate psicoamines and ribulosamines on the third carbon of their sugar moiety, thereby leading to the deglycation of the target amines.

    Gen-ID

    64122
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