Acetyl-CoA Carboxylase beta Antikörper (pSer220) (HRP)

Produktnummer ABIN1711110

Dieses Anti-Acetyl-CoA Carboxylase beta-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von Acetyl-CoA Carboxylase beta in ELISA, IHC (p) und IHC (fro). Geeignet für Human.

Kurzübersicht für Acetyl-CoA Carboxylase beta Antikörper (pSer220) (HRP) (ABIN1711110)

Target: Acetyl-CoA Carboxylase beta (ACACB)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Acetyl-CoA Carboxylase beta Antikörper ist konjugiert mit HRP

Applikation: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-Acetyl-CoA Carboxylase beta Antikörper (HRP)

Bindungsspezifität: pSer220

Homologie: Human

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from human Acetyl Coenzyme A Carboxylase beta around the phosphorylation site of Ser220

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu Acetyl-CoA Carboxylase beta

Target: Acetyl-CoA Carboxylase beta (ACACB)

Andere Bezeichnung: Acetyl Coenzyme A Carboxylase beta

Hintergrund:

Synonyms: Acetyl Coenzyme A Carboxylase beta phospho S220, Acetyl Coenzyme A Carboxylase beta phospho Ser2210 p-Acetyl Coenzyme A Carboxylase beta phospho S220, ACACB_HUMAN

Background: Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5' sequence and encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

UniProt: O00763

Pathways: AMPK Signaling, Ribonucleoside Biosynthetic Process