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Ly6c/CD59 Antikörper (AA 26-102) (HRP)

LY6C Reaktivität: Human WB, ELISA, IHC (fro), IHC (p) Wirt: Kaninchen Polyclonal HRP
Produktnummer ABIN1711072
  • Target Alle Ly6c/CD59 (LY6C) Produkte
    Ly6c/CD59 (LY6C) (Lymphocyte Antigen 6 Complex, Locus C (LY6C))
    Bindungsspezifität
    AA 26-102
    Reaktivität
    Human
    Wirt
    • 14
    Kaninchen
    Klonalität
    • 14
    Polyklonal
    Konjugat
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Ly6c/CD59 Antikörper ist konjugiert mit HRP
    Applikation
    • 14
    • 13
    • 13
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Kreuzreaktivität
    Human
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human Ly6c
    Isotyp
    IgG
  • Applikationshinweise
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Handhabung
    Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    Ly6c/CD59 (LY6C) (Lymphocyte Antigen 6 Complex, Locus C (LY6C))
    Andere Bezeichnung
    Ly6c/CD59 (LY6C Produkte)
    Hintergrund

    Synonyms: Ly 6c, Ly6c protein, Ly-6C, Ly6c1, Ly6c2, Lymphocyte antigen 6 complex, Lymphocyte antigen 6 complex locus C, Lymphocyte antigen 6C, Lymphocyte antigen 6C1, Lymphocyte antigen 6C2, Lymphocyte antigen Ly 6C, CD59_HUMAN.

    Background: The gene encoding the mouse alloantigen, Ly-6C, maps to chromosome 15 and encodes a 131 amino acid protein that belongs to the Ly-6 family of glycosyl-phosphatidylinositol (GPI)-linked proteins. Ly-6 family members share amino acid homology throughout a distinctive cysteine rich protein domain that incorporates O-linked carbohydrates. Murine Ly-6 Molecules have unique patterns of tissue expression during hematopoiesis from multipotential stem cells to lineage committed precursor cells, and on specific leukocyte subpopulations in the peripheral lymphoid tissues. Ly-6C is predominantly expressed on murine peripheral CD8 T cells. Ly-6C is involved in endothelial adhesion, the killing of target cells by CTLs, inducing TCR-mediated activation of IL-2 and IFN-?production in CD8 T cells and the homing of CD8 T cells. In addition, Ly-6C may act as a signaling molecule of LFA-1 activation.

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