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C1orf180 Antikörper (AA 21-100) (HRP)

C1ORF180 Reaktivität: Human WB, ELISA, IHC (fro), IHC (p) Wirt: Kaninchen Polyclonal HRP
Produktnummer ABIN1710900
  • Target Alle C1orf180 (C1ORF180) Produkte
    C1orf180 (C1ORF180) (Chromosome 1 Open Reading Frame 180 (C1ORF180))
    Bindungsspezifität
    AA 21-100
    Reaktivität
    Human
    Wirt
    • 14
    Kaninchen
    Klonalität
    • 14
    Polyklonal
    Konjugat
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser C1orf180 Antikörper ist konjugiert mit HRP
    Applikation
    • 14
    • 13
    • 13
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Homologie
    Human
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human C1orf180
    Isotyp
    IgG
  • Applikationshinweise
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Handhabung
    Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    C1orf180 (C1ORF180) (Chromosome 1 Open Reading Frame 180 (C1ORF180))
    Andere Bezeichnung
    C1orf180 (C1ORF180 Produkte)
    Synonyme
    long intergenic non-protein coding RNA 1555 antikoerper, LINC01555 antikoerper
    Hintergrund

    Synonyms: Chromosome 1 open reading frame 180, FLJ35487, Putative uncharacterized protein C1orf180, CA180_HUMAN.

    Background: Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8 % of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma. The C1orf180 gene product has been provisionally designated C1orf180 pending further characterization.

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