HES7 Antikörper (AA 21-100) (FITC)

Produktnummer ABIN1710531

Dieses Anti-HES7-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von HES7 in IF (cc) und IF (p). Geeignet für Human.

Kurzübersicht für HES7 Antikörper (AA 21-100) (FITC) (ABIN1710531)

Target: HES7 (Hairy and Enhancer of Split 7 (HES7))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HES7 Antikörper ist konjugiert mit FITC

Applikation: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-HES7 Antikörper (FITC)

Bindungsspezifität: AA 21-100

Homologie: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human HES7

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu HES7

Target: HES7 (Hairy and Enhancer of Split 7 (HES7))

Andere Bezeichnung: HES7

Hintergrund:

Synonyms: bHLH factor Hes7, bHLHb37, Class B basic helix loop helix protein 37, Class B basic helix-loop-helix protein 37, hairy and enhancer of split 7, Hes7, HES7_HUMAN, hHes7, SCDO4, Transcription factor HES 7, Transcription factor HES-7.

Background: HES7 is a 225 amino acid transcriptional repressor protein. Localized to the nucleus, HES7 represses transcription of N box- and E box-containing promoters. HES7, along with family member HES1, is thought to cooperatively regulate somite formation in the presomitic mesoderm. HES7 may also be essential for coordinated somite segmentation by acting as a segmentation clock. HES7 contains one basic helix-loop-helix (bHLH) domain and one Orange domain. Mutations in HES7 have been found to cause spondylocostal dysostosis, an autosomal recessive disorder characterized by deformities of the chest and spine.

Gen-ID: 84667