RUSC1 Antikörper (AA 281-380) (FITC)

Produktnummer ABIN1709593

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch RUSC1 in WB, IF (cc) und IF (p). Er zeigt eine Reaktivität gegenüber Human und Maus.

Kurzübersicht für RUSC1 Antikörper (AA 281-380) (FITC) (ABIN1709593)

Target: RUSC1 (RUN and SH3 Domain Containing 1 (RUSC1))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RUSC1 Antikörper ist konjugiert mit FITC

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-RUSC1 Antikörper (FITC)

Bindungsspezifität: AA 281-380

Kreuzreaktivität: Human, Maus

Homologie: Rat,Cow,Sheep,Pig

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human RUSC1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu RUSC1

Target: RUSC1 (RUN and SH3 Domain Containing 1 (RUSC1))

Andere Bezeichnung: Rusc1

Hintergrund:

Synonyms: DKFZp761A1822, Nesca, New molecule containing SH3 at the carboxy terminus, RUN and SH3 domain containing 1, RUN and SH3 domain containing protein 1, RUSC 1.

Background: RUSC1 is a 902 amino acid protein that contains a RUN domain and a SH3 domain. RUSC1?s RUN domain is necessary for NGF induced nuclear redistribution. RUSC1 is a putative signaling adapter which may play a role in neuronal differentiation. RUSC1 seems to be involved in signaling pathways that are regulated by the prolonged activation of MAPK. RUSC2 (RUN and SH3 domain containing 2), also known as Iporin, is a 1,516 amino acid cytoplasmic protein that is widely expressed, with highest levels in brain and testis. The RUN domain of RUSC2 is required for interaction with Rab 1A, Rab 1B and GM130. It is thought that RUSC2 may possibly function as a connector between endoplasmic reticulum (ER) derived vesicle targets triggered by the Rab 1 GTPases and a signaling pathway regulated by molecules containing SH3 and/or poly-proline regions. RUSC2 also consists of a SH3 domain, suggesting a role in protein-protein interactions.