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EYA2 Antikörper (AA 201-300) (Cy7)

This anti-EYA2 antibody (ABIN1708637) is a Rabbit Polyclonal antibody detecting EYA2 in WB, IF (cc), IF (p). Suitable for Rat.
Produktnummer ABIN1708637

Kurzübersicht für EYA2 Antikörper (AA 201-300) (Cy7) (ABIN1708637)

Target

Alle EYA2 Antikörper anzeigen
EYA2 (Eyes Absent Homolog 2 (Drosophila) (EYA2))

Reaktivität

  • 33
  • 18
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
Ratte

Wirt

  • 45
  • 3
Kaninchen

Klonalität

  • 45
  • 3
Polyklonal

Konjugat

  • 24
  • 4
  • 4
  • 4
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser EYA2 Antikörper ist konjugiert mit Cy7

Applikation

  • 39
  • 22
  • 12
  • 12
  • 7
  • 5
  • 5
  • 4
  • 3
  • 2
  • 2
Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • Bindungsspezifität

    • 14
    • 7
    • 6
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 201-300

    Kreuzreaktivität

    Ratte

    Homologie

    Human,Mouse,Dog,Cow,Sheep,Pig,Horse

    Aufreinigung

    Purified by Protein A.

    Immunogen

    KLH conjugated synthetic peptide derived from human EYA2

    Isotyp

    IgG
  • Applikationshinweise

    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 μg/μL

    Buffer

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    Konservierungsmittel

    ProClin

    Vorsichtsmaßnahmen

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    Haltbarkeit

    12 months
  • Target

    EYA2 (Eyes Absent Homolog 2 (Drosophila) (EYA2))

    Andere Bezeichnung

    EYA2

    Hintergrund

    Synonyms: EAB 1, EAB1, EYA 2, EYA2, EYA2_HUMAN, eyes absent 2 homolog Drosophila, Eyes absent homolog 2, Translation of this uORF probably lowers the translation efficiency of EYA2.

    Background: A gene on chromosome 20q13.1 encodes Eya2 (eyes absent). EYA2 is one of four members of the eyes absent family. A 271 amino acid domain at the carboxy-terminal is highly conserved amongst the members of the eyes absent family, while the PST (proline-serive-threonin)-rich amino-terminal is highly divergent. EYA2 is expressed relatively late in development in the cytoplasm of extensor tendons and ligaments of the phalangeal elements of the limb, cranial placodes, branchial arches, central nervous system, and the developing eye. Pax3 induces the expression of Eya2 in a cascade that is necessary and sufficient for myogenesis. EYA2, like EYA1, acts as a transcriptional activator in connective tissue patterning through its PST domain, which functions as a transactivation domain. EYA2 is translocated to the nucleus by Six proteins, which interact through their domain and homeodomain with EYA2. EYA2 carboxy-terminal interacts with the G Alpha z and G Alphai 2 proteins. This interaction prevents Six proteins from translocating EYA2 to the nucleus.

    Gen-ID

    2139
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