GCM2 Antikörper (AA 61-160) (Cy7)

Produktnummer ABIN1708343

Der Kaninchen Polyklonal Anti-GCM2-Antikörper wurde für WB, IF (cc) und IF (p) validiert. Er ist geeignet, GCM2 in Proben von Human zu detektieren.

Kurzübersicht für GCM2 Antikörper (AA 61-160) (Cy7) (ABIN1708343)

Target: GCM2 (Glial Cells Missing Homolog 2 (GCM2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GCM2 Antikörper ist konjugiert mit Cy7

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-GCM2 Antikörper (Cy7)

Bindungsspezifität: AA 61-160

Homologie: Human,Mouse,Rat,Dog,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GCM2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu GCM2

Target: GCM2 (Glial Cells Missing Homolog 2 (GCM2))

Andere Bezeichnung: GCM2

Hintergrund:

Synonyms: Chorion-specic transcription factor GCMb, GCM mot protein 2, GCMb, Glial cells missing homolog 2, glial cells missing homolog b, GCM2_HUMAN.

Background: Glial cells missing homolog 2 (GCM2), also known as Chorion-specific transcription factor GCMb, is a 506 amino acid nuclear protein. GCM2 is a transcription factor that acts as an essential regulator of parathyroid development. GCM2 is also thought to mediate the effect of calcium on parathyroid hormone expression and secretion in parathyroid cells. GCM2 contains one N-terminal GCM domain, which has DNA binding activity. Mutations of the gene that encodes GCM2 are associated with hypoparathyroidism, an autosomal recessive condition characterized by hypocalcemia and hyperphosphatemia.

Gen-ID: 9247

UniProt: O75603