Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

GCNT7 Antikörper (AA 241-430) (Cy7)

Dieses Anti-GCNT7-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von GCNT7 in WB, IF (cc) und IF (p). Geeignet für Human.
Produktnummer ABIN1707702

Kurzübersicht für GCNT7 Antikörper (AA 241-430) (Cy7) (ABIN1707702)

Target

Alle GCNT7 Antikörper anzeigen
GCNT7 (Glucosaminyl (N-Acetyl) Transferase Family Member 7 (GCNT7))

Reaktivität

  • 36
  • 4
  • 3
Human

Wirt

  • 36
Kaninchen

Klonalität

  • 36
Polyklonal

Konjugat

  • 12
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser GCNT7 Antikörper ist konjugiert mit Cy7

Applikation

  • 30
  • 13
  • 12
  • 12
  • 8
  • 7
  • 4
  • 4
  • 3
  • 1
Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • Bindungsspezifität

    • 14
    • 8
    • 5
    • 1
    • 1
    • 1
    • 1
    AA 241-430

    Homologie

    Human,Mouse,Rat,Horse

    Aufreinigung

    Purified by Protein A.

    Immunogen

    KLH conjugated synthetic peptide derived from human GCNT7

    Isotyp

    IgG
  • Applikationshinweise

    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 μg/μL

    Buffer

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    Konservierungsmittel

    ProClin

    Vorsichtsmaßnahmen

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    Haltbarkeit

    12 months
  • Target

    GCNT7 (Glucosaminyl (N-Acetyl) Transferase Family Member 7 (GCNT7))

    Andere Bezeichnung

    GCNT7

    Hintergrund

    Synonyms: 3-galactosyl-O-glycosyl-glycoprotein beta-1, 6-N-acetylglucosaminyltransferase 7, Beta-1, Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 7, C20orf105, GCNT, GCNT7, GCNT7_HUMAN, glucosaminyl N-acetyl transferase family member 7.

    Background: Belonging to the glycosyltransferase 14 family, GCNT7, also known as Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 7, is a 430 amino acid glycosyltransferase that is localized to the Golgi apparatus. Other members of this family include GCNT1, GCNT2, GCNT3, GCNT4 and GCNT6. GCNT1 has been shown to play an important regulatory role in the biosynthesis of mucin-type O-glycans, which serve as ligands in cell adhesion. Specifically, GCNT1 expression in leukocytes regulates the synthesis of core 2 O-glycans that carry sialyl-Lewis x (sLex) oligosaccharides, which confer high affinity binding to Selectin proteins. Since downregulation of Selectin ligand expression has been shown to inhibit tissue infiltration, glycosyltransferase 14 family members represent potential drug targets for the treatment of inflammatory disorders and other pathologies involving Selectin proteins.

    Gen-ID

    140687
Sie sind hier:
Chat with us!