GGA3 Antikörper (Golgi-Associated, gamma Adaptin Ear Containing, ARF Binding Protein 3) (Cy5)

Details for Product anti-GGA3 Antibody No. ABIN1705141
Antigen
  • C230037M19Rik
  • mKIAA0154
  • golgi associated, gamma adaptin ear containing, ARF binding protein 3
  • Gga3
  • GGA3
Reaktivität
Human, Maus, Ratte (Rattus)
60
27
25
6
4
3
2
2
2
2
2
2
2
2
1
1
1
Wirt
Kaninchen
37
20
3
2
Klonalität
Polyklonal
Konjugat
Dieser GGA3 Antikörper ist konjugiert mit Cy5
3
3
3
1
1
1
1
1
1
1
1
1
1
1
1
1
Applikation
Immunofluorescence (Paraffin-embedded Sections) (IF (p))
30
30
14
13
11
6
3
2
2
Optionen
Immunogen KLH conjugated synthetic peptide derived from human GGA3
Isotyp IgG
Reinigung Purified by Protein A.
Plasmids, Primers & others Plasmide, Primers & weitere GGA3 products on genomics-online (e.g. as negative or positive controls)
Antigen
Andere Bezeichnung Gga3 (GGA3 Antibody Abstract)
Hintergrund

The GGA family of proteins (Golgi-localized, g-Adaptin ear-containing, ARF-binding proteins) are ubiquitous coat proteins that facilitate the trafficking of soluble proteins from the trans-Golgi network (TGN) to endosomes/lysosomes by means of interactions with TGN-sorting receptors, ARF (ADP-ribosylation factor), and clathrin. Members of the GGA family, GGA1,GGA2 (also known as VEAR) and GGA3, are multi-domain proteins that bind mannose 6-phosphate receptors (MPRs). GGAs have modular structures with an N-terminal VHS (VPS27, Hrs and STAM) domain followed by a GAT (GGA and Tom1) domain, a connecting hinge segment and a C-terminal GAE (g-Adaptin ear) domain. The amino-terminal VHS domains of GGAs form complexes with the cytoplasmic domains of sorting receptors by recognizing acidic-cluster di-leucine (ACLL) sequences. The human GGA3 gene maps to chromosome 17 and encodes a 723 amino acid protein that shares 46 % sequence identity with GGA1 and 38 % with GGA2.

Synonyms: ADP ribosylation factor binding protein 3, ADP ribosylation factor binding protein GGA 3, ADP ribosylation factor binding protein GGA3, ADP-ribosylation factor-binding protein GGA3, ARF binding protein GGA 3, ARF binding protein GGA3, ARF-binding protein 3, gamma ear-containing, GGA 3, GGA3, GGA3_HUMAN, Golgi associated gamma adaptin ear containing ARF binding protein 3, Golgi localized gamma ear containing ARF binding protein 3, Golgi-localized, KIAA0154.

Gen-ID 23163
Applikations-hinweise IF(IHC-P) 1:50-200
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Lagerung 4 °C
Informationen zur Lagerung Store at 4°C
Haltbarkeit 12 months
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