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Aconitase 1 Antikörper (ACO1) (pSer138) (Cy5) Primary Antibody

ACO1 Reaktivität: Human, Maus, Ratte IF (p) Wirt: Kaninchen Polyclonal Cy5
Produktnummer ABIN1705082
$442.20
Zzgl. Versandkosten $45.00
100 μL
local_shipping Lieferung nach: Vereinigte Staaten von Amerika
Lieferung in 11 bis 16 Werktagen
  • Target
    Aconitase 1 (ACO1)
    Bindungsspezifität
    pSer138
    • 20
    • 16
    • 7
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Reaktivität
    Human, Maus, Ratte
    • 94
    • 64
    • 59
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Wirt
    Kaninchen
    Klonalität
    Polyklonal
    Konjugat
    Dieser Aconitase 1 Antikörper ist konjugiert mit Cy5
    • 51
    • 14
    • 7
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Applikation
    Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    • 66
    • 37
    • 25
    • 24
    • 13
    • 9
    • 8
    • 7
    • 6
    • 2
    • 1
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic phosphopeptide derived from human Aconitase 1 around the phosphorylation site of Ser138 [AD(p-S)LQ]
    Isotyp
    IgG
  • Applikationshinweise
    IF(IHC-P) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    4 °C
    Informationen zur Lagerung
    Store at 4°C
    Haltbarkeit
    12 months
  • Target
    Aconitase 1 (ACO1)
    Andere Bezeichnung
    Aconitase 1 (ACO1 Antibody Abstract)
    Synonyme
    ACONS, IREB1, IREBP, IREBP1, IRP1, Acon1, Ratireb, ratireb, Aco1, AI256519, Aco-1, Irebp, Irp1, aconitase 1, aconitase 1, soluble, aconitase 1 L homeolog, ACO1, Aco1, aco1.L
    Hintergrund

    Iron metabolism is essential for sustaining mammalian homeostasis. Iron uptake and distribution is a highly regulated process in mammalian cells that is monitored by two iron sensing proteins, iron regulatory protein-1 and -2 (IRP-1 and -2), also known as iron responsive element-binding protein-1 and -2 (IREâ€"BP-1 and -2) or aconitase 1 and 2. IRP-1 and IRP-2 are important soluble regulatory factors that mediate iron uptake and storage in mammalian cells. They are capable of either repressing translation or enhancing mRNA stability by associating with stem-loop motifs known as iron-responsive elements (IREs). IRPs respond to stress mediators, iron concentration and signaling factors, including nitrogen monoxide, cytokines and hydrogen peroxide.

    Synonyms: Aconitase 1 phospho S138, p-Aconitase 1 phospho S138, ACO 1, ACO1, ACOC_HUMAN, Aconitase 1 soluble, Aconitase, Aconitase1, Aconitate hydratase, ACONS, Citrate hydro lyase, Citrate hydro-lyase, Cytoplasmic aconitate hydratase, Ferritin repressor protein, IRE BP 1, IRE-BP 1, IREB 1, IREB1, IREBP, IREBP1, Iron regulatory protein 1, Iron responsive element binding protein 1, Iron-responsive element-binding protein 1, IRP 1, IRP1, OTTHUMP00000045233.

    Gen-ID
    48
    Pathways
    Transition Metal Ion Homeostasis
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