GNPTAB Antikörper (N-Acetylglucosamine-1-Phosphate Transferase, alpha and beta Subunits) (Cy5)

Details for Product anti-GNPTAB Antibody No. ABIN1705075
Antigen
  • si:ch211-234f20.3
  • wu:fd55d09
  • zgc:122985
  • zgc:158502
  • GNPTA
  • ICD
  • EG432486
  • mKIAA1208
  • RGD1564821
  • N-acetylglucosamine-1-phosphate transferase alpha and beta subunits
  • N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits
  • N-acetylglucosamine-1-phosphotransferase subunits alpha/beta
  • GNPTAB
  • gnptab
  • LOC100175423
  • Gnptab
Reaktivität
Human, Maus, Ratte (Rattus)
33
31
31
2
2
2
2
2
2
1
1
Wirt
Kaninchen
33
Klonalität
Polyklonal
Konjugat
Dieser GNPTAB Antikörper ist konjugiert mit Cy5
2
2
2
2
2
2
2
2
2
2
2
2
2
1
Applikation
Immunofluorescence (Paraffin-embedded Sections) (IF (p))
25
10
6
1
1
Optionen
Immunogen KLH conjugated synthetic peptide derived from human N-acetylglucosamine-1-phosphotransferase subunit alpha
Isotyp IgG
Reinigung Purified by Protein A.
Plasmids, Primers & others Plasmide, Primers & weitere GNPTAB products on genomics-online (e.g. as negative or positive controls)
Antigen
Andere Bezeichnung Gnptab (GNPTAB Antibody Abstract)
Hintergrund

This gene encodes two of three subunit types of the membrane-bound enzyme N-acetylglucosamine-1-phosphotransferase, a heterohexameric complex composed of two alpha, two beta, and two gamma subunits. The encoded protein is proteolytically cleaved at the Lys928-Asp929 bond to yield mature alpha and beta polypeptides while the gamma subunits are the product of a distinct gene (GeneID 84572). In the Golgi apparatus, the heterohexameric complex catalyzes the first step in the synthesis of mannose 6-phosphate recognition markers on certain oligosaccharides of newly synthesized lysosomal enzymes. These recognition markers are essential for appropriate trafficking of lysosomal enzymes. Mutations in this gene have been associated with both mucolipidosis II and mucolipidosis IIIA.[provided by RefSeq, May 2010].

Synonyms: N-acetylglucosamine-1-phosphotransferase subunit alpha, EC=2.7.8.17, GlcNAc-1-phosphotransferase subunits alpha/beta, GNPTA, GNPTA_HUMAN, Gnptab, KIAA1208, Stealth protein GNPTAB, UDP-N-acetylglucosamine-1-phosphotransferase subunits alpha/beta.

Applikations-hinweise IF(IHC-P) 1:50-200
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Lagerung 4 °C
Informationen zur Lagerung Store at 4°C
Haltbarkeit 12 months
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