GNL3L Antikörper (Guanine Nucleotide Binding Protein-Like 3 (Nucleolar)-Like) (Cy5)

Details for Product anti-GNL3L Antibody No. ABIN1704937
Antigen
  • SI:zK13A21.8
  • flj10613
  • flj10613l
  • si:dkey-13a21.8
  • zgc:110536
  • BC020354
  • guanine nucleotide binding protein-like 3 (nucleolar)-like
  • guanine nucleotide binding protein-like 3 (nucleolar)-like S homeolog
  • G protein nucleolar 3 like
  • gnl3l
  • gnl3l.S
  • GNL3L
  • Gnl3l
Reaktivität
Human, Maus, Ratte (Rattus)
65
21
18
7
3
3
3
2
1
Wirt
Kaninchen
65
Klonalität
Polyklonal
Konjugat
Dieser GNL3L Antikörper ist konjugiert mit Cy5
5
4
4
2
2
2
2
2
2
2
2
1
1
1
1
1
1
Applikation
Immunofluorescence (Paraffin-embedded Sections) (IF (p))
43
30
17
12
6
6
3
1
1
Optionen
Immunogen KLH conjugated synthetic peptide derived from human GNL3L
Isotyp IgG
Reinigung Purified by Protein A.
Plasmids, Primers & others Plasmide, Primers & weitere GNL3L products on genomics-online (e.g. as negative or positive controls)
Antigen
Andere Bezeichnung Gnl3l (GNL3L Antibody Abstract)
Hintergrund

GTPases from the MMR1/HSR1 GTP-binding protein subfamily are circularly rearranged G-motifs that play a critical role in maintaining normal cell growth. Deletion of these genes results in severe growth defects with a marked reduction in mature rRNA species and a concomitant accumulation of the 35S pre-rRNA transcript. Deletion also causes the ribosomal protein Rpl25a to fail exportation from the nucleolus. Deletion of any of the G-domain motifs will result in a null phenotype and nuclear/nucleolar localization that lacks the nucleolar export of preribosomes and is accompanied by a distortion of the nucleolar structure. GNL3L (guanine nucleotide binding protein-like 3 (nucleolar)-like) is a 582 amino acid nuclear protein that belongs to the MMR1/HSR1 GTP-binding protein family. Containing one G (guanine nucleotide-binding) domain, GNL3L is required for normal processing of ribosomal pre-rRNA and for cell proliferation.

Synonyms: GNL3L_HUMAN, FLJ10613, Guanine nucleotide binding protein-like 3 nucleolar-like, novel GTPase, OTTHUMP00000023374.

Gen-ID 54552
Applikations-hinweise IF(IHC-P) 1:50-200
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Lagerung 4 °C
Informationen zur Lagerung Store at 4°C
Haltbarkeit 12 months
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