GALNT13 Antikörper (UDP-N-Acetyl-alpha-D-Galactosamine:polypeptide N-Acetylgalactosaminyltransferase 13 (GalNAc-T13)) (Cy5)

Details for Product anti-GALNT13 Antibody No. ABIN1704912
Antigen
  • si:ch1073-215b15.1
  • A230002A12
  • A230020F20
  • BB182356
  • GalNAc-T13
  • H_NH0187G20.1
  • WUGSC:H_NH0187G20.1
  • T13
  • polypeptide N-acetylgalactosaminyltransferase 13
  • UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 13
  • polypeptide N-acetylgalactosaminyltransferase 13 S homeolog
  • GALNT13
  • galnt13
  • LOC100544871
  • Galnt13
  • galnt13.S
Reaktivität
Human, Maus, Ratte (Rattus)
44
30
20
4
4
4
3
2
1
1
Wirt
Kaninchen
37
7
Klonalität
Polyklonal
Konjugat
Dieser GALNT13 Antikörper ist konjugiert mit Cy5
3
3
3
2
2
2
1
1
1
1
1
1
1
1
1
1
Applikation
Immunofluorescence (Paraffin-embedded Sections) (IF (p))
33
19
12
3
Optionen
Immunogen KLH conjugated synthetic peptide derived from human GALNT13/GalNAc-T13
Isotyp IgG
Reinigung Purified by Protein A.
Plasmids, Primers & others Plasmide, Primers & weitere GALNT13 products on genomics-online (e.g. as negative or positive controls)
Antigen
Andere Bezeichnung Galnt13/Galnac-T13 (GALNT13 Antibody Abstract)
Hintergrund

The UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase (GalNAc-T) family of enzymes are substrate-specific proteins that catalyze the transfer of GalNAc (N-acetylgalactosamine) to serine and threonine residues onto various proteins, thereby initiating mucin-type O-linked glycosylation in the Golgi apparatus. GalNAc-T13 (Polypeptide N-acetylgalactosaminyltransferase 13), also known as UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 13, is a 556 amino acid protein that displays much stronger enzymatic activity than GalNAc-1 towards GalNAc transfer to mucin peptides such as Muc5a and Muc7. The N-terminal domain is involved in substrate binding and manganese coordination, while the C-terminal domain is involved in UDP-Gal binding and catalytic reaction. With specific expression in the central nervous system, GalNAc-T13 may be responsible for the synthesis of Tn antigen in neuronal cells, which is a universal carcinoma marker on malignant cells.

Synonyms: GalNAc T13, GalNAc transferase 13, N acetylgalactosaminyltransferase 13, Polypeptide GalNAc transferase 13, pp GaNTase 13, Protein UDP acetylgalactosaminyltransferase 13, UDP GalNAc:polypeptide N acetylgalactosaminyltransferase 13, UDP N acetyl alpha D galactosamine:polypeptide, GLT13_HUMAN.

Gen-ID 114805
Applikations-hinweise IF(IHC-P) 1:50-200
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Lagerung 4 °C
Informationen zur Lagerung Store at 4°C
Haltbarkeit 12 months
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