EYA2 Antikörper (Eyes Absent Homolog 2 (Drosophila)) (Cy5)

Details for Product anti-EYA2 Antibody No. ABIN1704868
Antigen
  • EYA2
  • zgc:92279
  • eab1
  • Eab1
  • EAB1
  • EYA transcriptional coactivator and phosphatase 2
  • EYA2
  • eya2
  • Eya2
Reaktivität
Human, Maus, Ratte (Rattus)
75
21
19
4
3
2
1
1
Wirt
Kaninchen
69
6
Klonalität
Polyklonal
Konjugat
Dieser EYA2 Antikörper ist konjugiert mit Cy5
7
6
6
2
2
2
2
2
2
2
2
1
1
1
1
1
1
Applikation
Immunofluorescence (Paraffin-embedded Sections) (IF (p))
51
38
12
10
8
6
2
Optionen
Immunogen KLH conjugated synthetic peptide derived from human EYA2
Isotyp IgG
Reinigung Purified by Protein A.
Plasmids, Primers & others Plasmide, Primers & weitere EYA2 products on genomics-online (e.g. as negative or positive controls)
Antigen
Andere Bezeichnung Eya2 (EYA2 Antibody Abstract)
Hintergrund

A gene on chromosome 20q13.1 encodes Eya2 (eyes absent). EYA2 is one of four members of the eyes absent family. A 271 amino acid domain at the carboxy-terminal is highly conserved amongst the members of the eyes absent family, while the PST (proline-serive-threonin)-rich amino-terminal is highly divergent. EYA2 is expressed relatively late in development in the cytoplasm of extensor tendons and ligaments of the phalangeal elements of the limb, cranial placodes, branchial arches, central nervous system, and the developing eye. Pax3 induces the expression of Eya2 in a cascade that is necessary and sufficient for myogenesis. EYA2, like EYA1, acts as a transcriptional activator in connective tissue patterning through its PST domain, which functions as a transactivation domain. EYA2 is translocated to the nucleus by Six proteins, which interact through their domain and homeodomain with EYA2. EYA2 carboxy-terminal interacts with the G Alpha z and G Alphai 2 proteins. This interaction prevents Six proteins from translocating EYA2 to the nucleus.

Synonyms: EAB 1, EAB1, EYA 2, EYA2, EYA2_HUMAN, eyes absent 2 homolog Drosophila, Eyes absent homolog 2, Translation of this uORF probably lowers the translation efficiency of EYA2.

Gen-ID 2139
Applikations-hinweise IF(IHC-P) 1:50-200
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Lagerung 4 °C
Informationen zur Lagerung Store at 4°C
Haltbarkeit 12 months
Haben Sie etwas anderes gesucht?