Fibulin 4 (FBLN4) Antikörper (Cy5)

Details zu Produkt Nr. ABIN1704858
Antigen
  • CB257
  • fbln4
  • fc56c09
  • id:ibd2923
  • sb:cb257
  • wu:fc56c09.x1
  • ARCL1B
  • FBLN4
  • MBP1
  • UPH1
  • 0610011K11Rik
  • Fbln4
  • FIBL-4
  • Fibulin-4
  • H411
  • EGF-containing fibulin-like extracellular matrix protein 2
  • EGF containing fibulin-like extracellular matrix protein 2b
  • fibulin 4
  • EGF containing fibulin like extracellular matrix protein 2
  • epidermal growth factor-containing fibulin-like extracellular matrix protein 2
  • Efemp2
  • efemp2b
  • fbln4
  • EFEMP2
Reaktivität
Human, Maus, Ratte (Rattus)
106
44
19
2
2
2
2
2
1
1
1
1
1
Wirt
Kaninchen
94
15
Klonalität
Polyklonal
Konjugat
Cy5
5
4
4
2
2
2
2
2
2
2
2
1
1
1
1
1
1
Applikation
Immunofluorescence (Paraffin-embedded Sections) (IF (p))
85
45
44
19
16
12
9
9
9
8
2
1
Optionen
Immunogen KLH conjugated synthetic peptide derived from human EFEMP2/Fibulin 4
Isotyp IgG
Reinigung Purified by Protein A.
Antigen
Andere Bezeichnung Efemp2/Fibulin 4 (FBLN4 Antibody Abstract)
Hintergrund

Fibulin proteins contribute to normal development of elastic fiber systems in various types of organs that require elasticity, such as vasculature, lung and skin. Fibulin-4, also known as EFEMP2 (EGF-containing fibulin-like extracellular matrix protein 2), MBP1 or UPH1 is a 443 amino acid secreted protein that contains six EGF-like calcium-binding domains and belongs to the fibulin family. Expressed ubiquitously with highest expression in heart, Fibulin-4 is essential for connective tissue development and elastic fiber formation, and may also play an important role in vascular patterning and collagen biosynthesis. Defects in the gene encoding Fibulin-4 are associated with autosomal recessive cutis laxa type I (CL type I), a connective tissue disorder that is inherited in both an autosomal dominant and an autosomal recessive manner and is characterized by inelastic tissue in all affected areas of the body.

Synonyms: EFEMP2, EGF containing fibulin like extracellular matrix protein 2, EGF-containing fibulin-like extracellular matrix protein 2, FBLN 4, FBLN4, FBLN4_HUMAN, FIBL 4, FIBL-4, FIBL4, Fibulin4, Fibulin-4, MBP 1, MBP1, Mutant p53 binding protein 1, Protein UPH1, UPH 1, UPH1, UPH1 protein.

Gen-ID 30008
Applikations-hinweise IF(IHC-P) 1:50-200
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Lagerung 4 °C
Informationen zur Lagerung Store at 4°C
Haltbarkeit 12 months
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