Polymerase (DNA Directed) kappa (POLK) Antikörper (Cy5)

Details zu Produkt Nr. ABIN1704852
Antigen
  • DINB1
  • DINP
  • POLQ
  • Dinb1
  • POLK
  • si:ch211-254o18.3
  • DNA polymerase kappa
  • polymerase (DNA directed) kappa
  • polymerase (DNA directed), kappa
  • polymerase (DNA directed) kappa L homeolog
  • POLK
  • Polk
  • polk
  • Tb11.01.0080
  • Tb11.01.0010
  • Tb11.01.0020
  • Tb11.01.0030
  • Tb11.01.0040
  • Tb11.01.0050
  • Tb11.12.0001
  • Tb11.12.0002
  • Tb11.12.0003
  • polk.L
  • polk-1
Reaktivität
Human, Maus, Ratte (Rattus)
97
46
40
4
4
4
4
4
2
1
1
1
1
Wirt
Kaninchen
78
12
10
Klonalität
Polyklonal
Konjugat
Cy5
5
4
4
2
2
2
2
2
2
2
2
1
1
1
1
1
1
Applikation
Immunofluorescence (Paraffin-embedded Sections) (IF (p))
78
39
17
12
12
12
3
2
1
1
Optionen
Immunogen KLH conjugated synthetic peptide derived from human DNA Polymerase Kappa/POLK
Isotyp IgG
Reinigung Purified by Protein A.
Antigen
Andere Bezeichnung Dna Polymerase kappa/polk (POLK Antibody Abstract)
Hintergrund

DNA polymerase lambda (pol Kappa), also designated DNA polymerase Kappa or Pol Beta2, is a low-fidelity polymerase which plays a role in both spontaneous and DNA damage-induced mutagenesis. Encoded by the POLL gene, pol Kappa is a member of the DNA polymerase type-X family. Pol Kappa extends primer-terminal mispairs opposite nondamaged DNA templates, suggesting that it may assist in extending mismatched base pairs during normal DNA replication. In addition, pol Kappa may play a role in the mutagenic bypass of T-T dimers. Proliferating cell nuclear antigen (PCNA), a protein essential to DNA replication, interacts with pol Kappa and thus influences the ability of pol Kappa to synthesize DNA.

Synonyms: DNA polymerase kappa, DINB protein, Short=DINP, POLK_HUMAN.

Gen-ID 51426
Pathways DNA Reparatur
Applikations-hinweise IF(IHC-P) 1:50-200
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Lagerung 4 °C
Informationen zur Lagerung Store at 4°C
Haltbarkeit 12 months
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