Eukaryotic Translation Initiation Factor 2C3 (EIF2C3) Antikörper (Cy5)

Details zu Produkt Nr. ABIN1704781
Antigen
  • EIF2C3
  • Eif2c3
  • Argonaute3
  • ago3
  • eif2c3
  • eif2c3b
  • si:dkey-3n22.3
  • AW048688
  • C130014L07Rik
  • ARGONAUTE 3
  • T19E23.8
  • T19E23_8
  • argonaute 3, RISC catalytic component
  • argonaute RISC catalytic component 3b
  • argonaute RISC catalytic subunit 3
  • argonaute RISC catalytic component 3
  • ARGONAUTE 3
  • AGO3
  • Ago3
  • ago3b
Reaktivität
Human, Maus, Ratte (Rattus)
43
32
29
4
4
4
4
4
4
2
2
2
1
1
Wirt
Kaninchen
38
5
Klonalität
Polyklonal
Konjugat
Cy5
2
2
2
2
2
2
1
1
1
1
1
1
1
1
Applikation
Immunofluorescence (Paraffin-embedded Sections) (IF (p))
21
12
8
4
4
3
3
2
1
Optionen
Immunogen KLH conjugated synthetic peptide derived from human Argonaute 3/eIF2C3
Isotyp IgG
Reinigung Purified by Protein A.
Antigen
Andere Bezeichnung Argonaute 3/Eif2c3 (EIF2C3 Antibody Abstract)
Hintergrund

Eukaryotic translation initiation factor 2C (eIF2C) proteins (argonaute family) influence RNA interference (RNAi) as components of the RNA-inducible silencing complex (RISC) or microRNA (miRNA)-containing ribonucleoprotein particle (miRNP). Small RNAs, including small interfering RNAs (siRNAs) and miRNAs, can silence target genes through mechanisms that utilize RISC or miRNP particles. eIF2C1 (argonaute 1, AGO1, eIF2C, GERP95, Q99) and Dicer1 play a coordinated role in siRNA-mediated gene silencing. eIF2C2 (Slicer, argonaute 2, AGO2, Q10) is a RISC component that can concentrate in cytoplasmic processing bodies (P-bodies) and catalyze mRNA cleavage. Mammalian P-bodies contain mRNAs and have an association with miRNA-induced translational silencing and siRNA-induced mRNA degradation. Additional eIF2C proteins include eIF2C3 (argonaute 3, AGO3), eIF2C4 (argonaute 4, AGO4) and meIF2c5 (mouse argonaute 5).

Synonyms: Argonaute 3/e2C 3, 5730550L01Rik, Ago 3, Ago3, AGO3_HUMAN, argonaute 3, Argonaute3, e 2C 3, e-2C 3, e2C 3, E2c3, e2C3, E2C3 protein, Eukaryotic translation initiation factor 2C 3, Eukaryotic translation initiation factor 2C3, FLJ12765, hAgo3, MGC86946, Protein argonaute-3.

Gen-ID 192669
Pathways Fc-epsilon Rezeptor Signalübertragung, Regulatorische RNA Pathways, EGFR Signaling Pathway, Neurotrophin Signalübertragung
Applikations-hinweise IF(IHC-P) 1:50-200
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Lagerung 4 °C
Informationen zur Lagerung Store at 4°C
Haltbarkeit 12 months
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