Telefon:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antikoerper-online.de

Argininosuccinate Lyase (ASL) Antikörper (Cy5) Primary Antibody

ASL Reaktivität: Human, Maus, Ratte IF (p) Wirt: Kaninchen Polyclonal Cy5
Produktnummer ABIN1704717
$442.20
Zzgl. Versandkosten $45.00
100 μL
local_shipping Lieferung nach: Vereinigte Staaten von Amerika
Lieferung in 11 bis 16 Werktagen
  • Target
    Argininosuccinate Lyase (ASL)
    Reaktivität
    Human, Maus, Ratte
    • 53
    • 30
    • 24
    • 6
    • 6
    • 6
    • 6
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    Wirt
    Kaninchen
    Klonalität
    Polyklonal
    Konjugat
    Cy5
    • 30
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Applikation
    Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    • 31
    • 12
    • 10
    • 8
    • 8
    • 7
    • 7
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human ASL/Argininosuccinate Lyase
    Isotyp
    IgG
  • Applikationshinweise
    IF(IHC-P) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    4 °C
    Informationen zur Lagerung
    Store at 4°C
    Haltbarkeit
    12 months
  • Target
    Argininosuccinate Lyase (ASL)
    Andere Bezeichnung
    Asl/Argininosuccinate Lyase (ASL Antibody Abstract)
    Synonyme
    ASAL, 2510006M18Rik, zgc:63532, BA4879, PSPTO0125, Adl, Asl, argininosuccinate lyase, argininosuccinate lyase ArgH, adenylosuccinate lyase, argininosuccinate lyase L homeolog, ASL, Asl, asl, argH2, argH, arg7, CNC04420, STHERM_c13370, Adsl, asl.L, ARG7
    Hintergrund

    ASL is a member of the lyase 1 family of proteins and is predominantly expressed in the liver. Localizing to the cytoplasm and existing as a homotetramer, ASL catalyzes the hydrolytic cleavage of argininosuccinic acid (ASA) to fumarate and arginine, an essential step of the urea cycle which is crucial for the detoxification of ammonia. This reaction is also involved in the biosynthesis of arginine. In addition, ASL shares high sequence homology with the avian and reptilian eye lens protein, d-crystallin. Mutations in the gene encoding ASL leads to an accumulation of ASA in body fluids and results in Arginosuc-cinic aciduria (ASAuria), an autosomal recessive disorder that is characterized by hyperammonemia, liver enlargement, convulsions, physical and mental retardation, episodic unconsciousness and dry and brittle hair showing trich-orrhexis nodosa (weak points or nodes in the hair shaft).

    Synonyms: Argininosuccinase, Argininosuccinate lyase, Arginosuccinase, ARLY_HUMAN, ASAL, ASL, EC 4.3.2.1.

    Gen-ID
    435
    Pathways
    Response to Growth Hormone Stimulus
Sie sind hier:
help Kundenservice