ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 7 (ABCB7) Antikörper (Cy5)

Details zu Produkt Nr. ABIN1704708
Antigen
  • CG7955
  • Dmel\\CG7955
  • dABCB7
  • GB11034
  • ABCB7
  • fc20c02
  • wu:fc20c02
  • ABC7
  • ASAT
  • Atm1p
  • EST140535
  • AA517758
  • AU019072
  • Abc7
  • ATP binding cassette subfamily B member 7
  • ATP-binding cassette sub-family B member 7, mitochondrial
  • ATP-binding cassette, sub-family B (MDR/TAP), member 7
  • ATP-binding cassette sub-family B member 7, mitochondrial-like
  • ABCB7
  • LOC412749
  • abcb7
  • LOC100367778
  • LOC100467128
  • Abcb7
Reaktivität
Human, Maus, Ratte (Rattus)
86
33
31
2
1
1
1
1
1
1
1
1
1
1
Wirt
Kaninchen
88
Klonalität
Polyklonal
Konjugat
Cy5
5
3
3
2
2
2
2
2
1
1
1
1
1
1
1
1
1
Applikation
Immunofluorescence (Paraffin-embedded Sections) (IF (p))
51
43
42
13
12
4
3
2
1
Optionen
Immunogen KLH conjugated synthetic peptide derived from human ABCB7
Isotyp IgG
Reinigung Purified by Protein A.
Antigen
Andere Bezeichnung Abcb7 (ABCB7 Antibody Abstract)
Hintergrund

The peroxisomal membrane contains several ATP-binding cassette (ABC) transporters, ABCD1â€"4 that are known to be present in the human peroxisome membrane (1). All four proteins are ABC half-transporters, which dimerize to form an active transporter (1). A mutation in the ABCD1 causes X-linked adrenoleukodystrophy (X-ALD), a peroxisomal disorder which affects lipid storage (2,3). ABCD2 in mouse, is expressed at high levels in the brain and adrenal organs, which are adversely affected in X-ALD (4). The peroxisomal membrane comprises 2 quantitatively major proteins, PMP22 and ABCD3 (5). ABCD3 is associated with irregularly shaped vesicles which may be defective peroxisomes or peroxisome precursors (5). ABCD4 localizes to peroxisomes (1). The genes which encode ABCD1â€"4 map to human chromosome Xq28, 12q11-q12, 1p22-p21 and 14q24.3, respectively (3,6â€"8). ABCB7 is a half-transporter involved in the transport of heme from the mitochondria to the cytosol and maps to human chromosome Xq13.1-q13.3 (9).

Subcellular location: Cytoplasm

Synonyms: ABC transporter 7 protein, ABC7, Abcb7, ABCB7_HUMAN, ASAT, Atm1p, ATP binding cassette 7, ATP binding cassette sub family B MDR/TAP member 7, ATP binding cassette sub family B member 7, ATP binding cassette sub family B member 7 mitochondrial, ATP binding cassette transporter 7, ATP-binding cassette sub-family B member 7, ATP-binding cassette transporter 7, EST140535, MDR7, mitochondrial, Multidrug resistance protein 7, P-glycoprotein 7, PGP7.

Gen-ID 22
Pathways Transition Metal Ion Homeostasis
Applikations-hinweise IF(IHC-P) 1:50-200
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Lagerung 4 °C
Informationen zur Lagerung Store at 4°C
Haltbarkeit 12 months
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