VGF Antikörper (VGF Nerve Growth Factor Inducible) (Cy5)

Details for Product anti-VGF Antibody No. ABIN1704687
Antigen
  • VGF
  • Gm1052
  • VGF nerve growth factor inducible
  • VGF
  • Vgf
Reaktivität
Human, Maus, Ratte (Rattus)
114
82
82
5
3
2
2
1
1
1
1
Wirt
Kaninchen
119
4
Klonalität
Polyklonal
Konjugat
Dieser VGF Antikörper ist konjugiert mit Cy5
10
7
4
4
4
4
4
3
3
3
2
2
2
2
2
1
Applikation
Immunofluorescence (Paraffin-embedded Sections) (IF (p))
64
42
37
25
23
7
5
5
5
2
2
1
Optionen
Immunogen KLH conjugated synthetic peptide derived from human NERP2
Isotyp IgG
Reinigung Purified by Protein A.
Plasmids, Primers & others Plasmide, Primers & weitere VGF products on genomics-online (e.g. as negative or positive controls)
Antigen
Andere Bezeichnung VGF/NERP2 (VGF Antibody Abstract)
Hintergrund

This gene is specifically expressed in a subpopulation of neuroendocrine cells, and is upregulated by nerve growth factor. The structural organization of this gene is similar to that of the rat gene, and both the translated and the untranslated regions show a high degree of sequence similarity to the rat gene. The encoded secretory protein also shares similarities with the secretogranin/chromogranin family, however, its exact function is not known. Nerve growth factor (NGF) is a peptide that plays a key role in the differentiation and survival of neurons in the peripheral nervous system (PNS) and the central nervous system (CNS). VGF is a peptide synthesized and secreted by neurons and is upregulated by NGF in the PC12 cell line. VGF is widely expressed in both the PNS and CNS, but is especially abundant in the adult hypothalamus. VGF plays an essential role in how the brain regulates energy expenditure and body weight. Its expression is rapidly induced by injury, the circadian clock, and neuronal activity.

Subcellular location: Nucleus

Synonyms: NERP-2, Nerve growth factor inducible, Neuroendocrine regulatory peptide-2, Neurosecretory protein VGF, VGF, VGF_HUMAN.

Gen-ID 7425
Pathways Hormone Transport, Carbohydrate Homeostasis
Applikations-hinweise IF(IHC-P) 1:50-200
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Lagerung 4 °C
Informationen zur Lagerung Store at 4°C
Haltbarkeit 12 months
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