FMN1 Antikörper (Formin 1) (Cy5)

Details for Product anti-FMN1 Antibody No. ABIN1704658
Antigen
  • si:dkey-81b15.10
  • fmn
  • formin
  • FMN
  • LD
  • BB164513
  • Fmn
  • formin-1
  • ld
  • RGD1306349
  • RGD1310100
  • formin 1
  • fmn1
  • FMN1
  • Fmn1
Reaktivität
Human, Maus, Ratte (Rattus)
32
19
16
Wirt
Kaninchen
30
4
Klonalität
Polyklonal
Konjugat
Dieser FMN1 Antikörper ist konjugiert mit Cy5
1
1
1
1
1
1
1
1
1
1
1
1
1
Applikation
Immunofluorescence (Paraffin-embedded Sections) (IF (p))
21
12
6
4
2
1
1
Optionen
Immunogen KLH conjugated synthetic peptide derived from human FMN1/Formin 1
Isotyp IgG
Reinigung Purified by Protein A.
Plasmids, Primers & others Plasmide, Primers & weitere FMN1 products on genomics-online (e.g. as negative or positive controls)
Antigen
Andere Bezeichnung Fmn1/Formin 1 (FMN1 Antibody Abstract)
Hintergrund

The temporal genetic hierarchy influencing normal limb development can deregulate and mediate mammalian developmental syndromes. In mice, the limb deformity (ld) locus influences normal limb development and gives rise to alternative mRNAs that can translate into a family of proteins known as formins. Formins play a crucial role in cytoskeletal reorganization by influencing Actin filament assembly. Formins co-localize with the actin cytoskeleton and can translocate into the cell cytosol and into the nucleus in an HGF-dependent manner. Vertebrate nuclear formins can control polarizing activity in limb buds through establishment of a Sonic hedgehog/FGF-4 feedback loop. Deficiency mutations at the mammalian ld locus lead to profound developmental defects in limb and kidney formation. The human Formin 1 and 2 genes map to chromosome 15q13.3 and 1q43, respectively.

Synonyms: FMN, Formin 1, Formin1, Formin-1, LD, Limb deformity protein homolog, FMN1_HUMAN.

Gen-ID 342184
Pathways Regulation of Actin Filament Polymerization
Applikations-hinweise IF(IHC-P) 1:50-200
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Lagerung 4 °C
Informationen zur Lagerung Store at 4°C
Haltbarkeit 12 months
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