ABLIM3 Antikörper (Actin Binding LIM Protein Family, Member 3) (Cy5)

Details for Product anti-ABLIM3 Antibody No. ABIN1704606
Antigen
  • AW990719
  • D930036B08Rik
  • RGD1565118
  • actin binding LIM protein family member 3
  • actin binding LIM protein family, member 3
  • ABLIM3
  • Ablim3
Reaktivität
Human, Maus, Ratte (Rattus)
50
22
22
Wirt
Kaninchen
46
4
Klonalität
Polyklonal
Konjugat
Dieser ABLIM3 Antikörper ist konjugiert mit Cy5
5
4
4
2
2
2
2
2
2
2
2
1
1
1
1
1
1
Applikation
Immunofluorescence (Paraffin-embedded Sections) (IF (p))
28
18
13
4
2
Optionen
Immunogen KLH conjugated synthetic peptide derived from human ABLIM3
Isotyp IgG
Reinigung Purified by Protein A.
Plasmids, Primers & others Plasmide, Primers & weitere ABLIM3 products on genomics-online (e.g. as negative or positive controls)
Antigen
Andere Bezeichnung Ablim3 (ABLIM3 Antibody Abstract)
Hintergrund

The ABLIM1 protein has an N-terminal domain that contains four double zinc finger motifs, which conform to the LIM motif consensus sequence. ABLIM1 binds to F-Actin through a dematin-like domain and is expressed in retina, brain and muscle tissue. There are four known isoforms of ABLIM1. The gene encoding ABLIM1 maps to a region of chromosome 10 associated with frequent loss of heterozygosity in human tumors, thus identifying ABLIM1 as a candidate tumor suppressor gene. ABLIM2 and ABLIM3 show highest expression in muscle and neuronal tissues, bind to F-Actin, and are localized on stress fibers. They also have been shown to enhance STARS (striated muscle activator of Rho signaling) dependent activation of serum-response factor (SRF), thereby modulating transcription.

Synonyms: abLIM-3, Ablim3, ABLM3_HUMAN, Actin binding LIM protein 3, Actin binding LIM protein family member 3, Actin-binding LIM protein 3, Actin-binding LIM protein family member 3, HMFN1661, KIAA0843.

Gen-ID 22885
Applikations-hinweise IF(IHC-P) 1:50-200
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Lagerung 4 °C
Informationen zur Lagerung Store at 4°C
Haltbarkeit 12 months
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