Gem (Nuclear Organelle) Associated Protein 4 (GEMIN4) Antikörper (Cy5)

Details zu Produkt Nr. ABIN1704576
Antigen
  • HC56
  • HCAP1
  • HHRF-1
  • p97
  • 4932415L08Rik
  • AU015359
  • im:7143815
  • wu:fc41c09
  • zgc:110169
  • GEMIN4
  • RGD1563715
  • gem nuclear organelle associated protein 4
  • gem (nuclear organelle) associated protein 4
  • GEMIN4
  • Gemin4
  • gemin4
Reaktivität
Human, Maus, Ratte (Rattus)
61
21
15
2
2
1
1
1
1
1
Wirt
Kaninchen
56
5
Klonalität
Polyklonal
Konjugat
Cy5
5
4
4
2
2
2
2
2
2
2
2
1
1
1
1
1
1
Applikation
Immunofluorescence (Paraffin-embedded Sections) (IF (p))
38
28
12
5
3
3
3
1
Optionen
Immunogen KLH conjugated synthetic peptide derived from human Gemin 4
Isotyp IgG
Reinigung Purified by Protein A.
Antigen
Andere Bezeichnung Gemin 4 (GEMIN4 Antibody Abstract)
Hintergrund

Gemin4 is a component of the SMN core complex which, while in the cytoplasm, plays an essential role in ribonucleoprotein (snRNP) assembly, including the biogenesis, delivery and recycling of snRNPs to the spliceosome. In the nucleus, where SMN is required for pre-mRNA splicing, Gemin4 concentrates next to coiled bodies in subnuclear structures called gems, that are highly enriched in splicosomal snRNPs, and in the nucleolus. Deletion or loss-of-function mutations in the SMN lead to the neurodegenerative disease spinal muscular atrophy (SMA). The human Gemin4 maps to chromosome 17p13.

Synonyms: Gemin4, Gemin-4, Component of gems 4, Gem associated protein 4, HC56, HHRF 1, GEMI4_HUMAN.

Gen-ID 50628
Pathways Ribonucleoprotein Complex Subunit Organization
Applikations-hinweise IF(IHC-P) 1:50-200
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Lagerung 4 °C
Informationen zur Lagerung Store at 4°C
Haltbarkeit 12 months
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