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EXTL3 Antikörper (AA 351-450) (Cy5)

EXTL3 Reaktivität: Ratte WB, IF (cc), IF (p) Wirt: Kaninchen Polyclonal Cy5
Produktnummer ABIN1704562
  • Target Alle EXTL3 Antikörper anzeigen
    EXTL3 (Exostoses (Multiple)-Like 3 (EXTL3))
    Bindungsspezifität
    • 14
    • 14
    • 7
    • 5
    • 5
    • 5
    • 5
    • 2
    • 1
    • 1
    • 1
    AA 351-450
    Reaktivität
    • 45
    • 15
    • 10
    • 1
    Ratte
    Wirt
    • 59
    Kaninchen
    Klonalität
    • 58
    Polyklonal
    Konjugat
    • 19
    • 6
    • 6
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Dieser EXTL3 Antikörper ist konjugiert mit Cy5
    Applikation
    • 48
    • 31
    • 27
    • 12
    • 12
    • 10
    • 9
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Kreuzreaktivität
    Ratte
    Homologie
    Human,Mouse,Dog,Horse
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human EXTL3
    Isotyp
    IgG
    Top Product
    Discover our top product EXTL3 Primärantikörper
  • Applikationshinweise
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    EXTL3 (Exostoses (Multiple)-Like 3 (EXTL3))
    Andere Bezeichnung
    EXTL3 (EXTL3 Produkte)
    Synonyme
    BcDNA:LD21192 antikoerper, Botv antikoerper, CG15110 antikoerper, DEXT3 antikoerper, DEXTL3 antikoerper, Dextl3 antikoerper, Dmel\\CG15110 antikoerper, Extl3 antikoerper, 2900009G18Rik antikoerper, AU040105 antikoerper, Ext1l antikoerper, mKIAA0519 antikoerper, BOTV antikoerper, EXTL1L antikoerper, EXTR1 antikoerper, REGR antikoerper, RPR antikoerper, Regr antikoerper, brother of tout-velu antikoerper, exostoses (multiple)-like 3 antikoerper, exostosin like glycosyltransferase 3 antikoerper, exostosin-like glycosyltransferase 3 antikoerper, botv antikoerper, Extl3 antikoerper, EXTL3 antikoerper
    Hintergrund

    Synonyms: botv, DKFZp686C2342, Exostoses multiple-like 3, Exostoses-like 3, Exostosin-like 3, EXT-related protein 1, EXTL1L, EXTL3, EXTL3_HUMAN, EXTR1, Glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferas, Glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase, Hereditary multiple exostoses gene isolog, KIAA0519, Multiple exostosis-like protein 3, Putative tumor suppressor protein EXTL3, REG, Reg receptor, REGR, RPR.

    Background: EXTL3 is a member of the EXT (hereditary multiple exostosin) gene family of tumor suppressors encoding glycosyltransferases involved in heparan sulfate (HS) biosynthesis. Within this family, the C-terminus is conserved between all members from C. elegans to vertebrates. EXTL3 is a ubiquitously expressed, developmentally regulated, single-pass type II membrane protein that localizes to the endoplasmic reticulum membrane. EXTL3 adds N-acetylglucosamine (GlcNAc) to the polysaccharide-protein linkage region and to the growing HS chain suggesting that it plays a role in both the initiation and elongation of HS chains. In addition, EXTL3 may act as a Reg receptor, binding Reg via its N-terminus.

    Gen-ID
    2137
    Pathways
    Glycosaminoglycan Metabolic Process, ER-Nucleus Signaling
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