Exostoses (Multiple)-Like 3 (EXTL3) Antikörper (Cy5)

Details zu Produkt Nr. ABIN1704562
Antigen
  • BcDNA:LD21192
  • Botv
  • CG15110
  • DEXT3
  • DEXTL3
  • Dextl3
  • Dmel\\CG15110
  • Extl3
  • 2900009G18Rik
  • AU040105
  • Ext1l
  • mKIAA0519
  • BOTV
  • EXTL1L
  • EXTR1
  • REGR
  • RPR
  • Regr
  • brother of tout-velu
  • exostoses (multiple)-like 3
  • exostosin like glycosyltransferase 3
  • exostosin-like glycosyltransferase 3
  • botv
  • Extl3
  • EXTL3
Reaktivität
Human, Maus, Ratte (Rattus)
98
36
26
1
Wirt
Kaninchen
98
Klonalität
Polyklonal
Konjugat
Cy5
9
7
7
4
4
4
3
3
3
3
3
2
1
1
1
1
1
Applikation
Immunofluorescence (Paraffin-embedded Sections) (IF (p))
66
53
52
15
12
10
1
1
Optionen
Immunogen KLH conjugated synthetic peptide derived from human EXTL3
Isotyp IgG
Reinigung Purified by Protein A.
Antigen
Andere Bezeichnung Extl3 (EXTL3 Antibody Abstract)
Hintergrund

EXTL3 is a member of the EXT (hereditary multiple exostosin) gene family of tumor suppressors encoding glycosyltransferases involved in heparan sulfate (HS) biosynthesis. Within this family, the C-terminus is conserved between all members from C. elegans to vertebrates. EXTL3 is a ubiquitously expressed, developmentally regulated, single-pass type II membrane protein that localizes to the endoplasmic reticulum membrane. EXTL3 adds N-acetylglucosamine (GlcNAc) to the polysaccharide-protein linkage region and to the growing HS chain suggesting that it plays a role in both the initiation and elongation of HS chains. In addition, EXTL3 may act as a Reg receptor, binding Reg via its N-terminus.

Synonyms: botv, DKFZp686C2342, Exostoses multiple-like 3, Exostoses-like 3, Exostosin-like 3, EXT-related protein 1, EXTL1L, EXTL3, EXTL3_HUMAN, EXTR1, Glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferas, Glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase, Hereditary multiple exostoses gene isolog, KIAA0519, Multiple exostosis-like protein 3, Putative tumor suppressor protein EXTL3, REG, Reg receptor, REGR, RPR.

Gen-ID 2137
Pathways Glycosaminoglycan Metabolic Process, ER-Nucleus Signaling
Applikations-hinweise IF(IHC-P) 1:50-200
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Lagerung 4 °C
Informationen zur Lagerung Store at 4°C
Haltbarkeit 12 months
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