EIF2A Antikörper (Eukaryotic Translation Initiation Factor 2A, 65kDa) (AA 50-91) (Cy5)

Details for Product anti-EIF2A Antibody No. ABIN1704529
Antigen
  • ATEIF2-A2
  • EIF2-A2
  • eukaryotic translation initiation factor 2 alpha subunit
  • EIF-2A
  • MST089
  • MSTP004
  • MSTP089
  • D030048D22
  • D3Ertd194e
  • im:7145971
  • zgc:110460
  • DDBDRAFT_0185936
  • DDBDRAFT_0234177
  • DDB_0185936
  • DDB_0234177
  • Eif2a
  • eif2a
  • eif2alpha
  • EIF2A
  • CG9946
  • Dmel\\CG9946
  • Eif2alpha
  • IF2A_DROME
  • M(1)14C
  • M(1)19-153
  • M(1)8e3-10
  • deIF2alpha
  • eIF-2
  • eIF-2 a
  • eIF-2 alpha
  • eIF2 alpha
  • eIF2-alpha
  • eIF2a
  • eIF2alpha
  • eiF-2alpha
  • elF2alpha
  • l(1)14Cf
  • l(1)19-153
  • eukaryotic translation initiation factor 2 alpha subunit
  • eukaryotic translation initiation factor 2A
  • eukaryotic translation initiation factor 2A, 65kDa
  • eukaryotic translation initiation factor 2A S homeolog
  • eukaryotic translation initiation factor
  • eukaryotic translation Initiation Factor 2alpha
  • EIF2 ALPHA
  • EIF2A
  • Eif2a
  • eif2a
  • eIF2a
  • eif2a.S
  • eif2A
  • eIF-2alpha
Epitop
AA 50-91, pSer52
18
12
12
11
11
9
8
8
8
8
6
5
3
2
2
2
2
2
1
1
1
1
1
1
Reaktivität
Human, Maus, Ratte (Rattus)
155
89
82
8
5
3
2
2
1
1
1
1
1
1
Wirt
Kaninchen
133
23
Klonalität
Polyklonal
Konjugat
Dieser EIF2A Antikörper ist konjugiert mit Cy5
7
5
5
5
4
4
4
3
3
2
2
2
2
2
2
2
Applikation
Immunofluorescence (Paraffin-embedded Sections) (IF (p))
106
83
48
33
31
19
15
7
5
4
1
1
Optionen
Immunogen KLH conjugated synthetic phosphopeptide derived from human eIF2 alpha subunit 1 around the phosphorylation site of Ser52 [EL(p-S)RR]
Isotyp IgG
Reinigung Purified by Protein A.
Plasmids, Primers & others Plasmide, Primers & weitere EIF2A products on genomics-online (e.g. as negative or positive controls)
Antigen
Andere Bezeichnung eIF2 alpha (EIF2A Antibody Abstract)
Hintergrund

Functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 4S ribosomal subunit, followed by mRNA binding to form a 43S preinitiation complex. Junction of the 6S ribosomal subunit to form the 8S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex. In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 must exchange with GTP by way of a reaction catalyzed by eIF-2B.

Subcellular location: Cytoplasm

Synonyms: EIF2, EIF-2, EIF2A, EIF-2A, EIF-2alpha, Eukaryotic translation initiation factor 2 subunit 1, Eukaryotic translation initiation factor 2 subunit alpha, eIF-2-alpha, EIF2S1

Gen-ID 1965
UniProt P05198
Pathways Ribonucleoprotein Complex Subunit Organization, ER-Nucleus Signaling, Hepatitis C, Methionine Biosynthetic Process, Ribosome Assembly
Applikations-hinweise IF(IHC-P) 1:50-200
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Lagerung 4 °C
Informationen zur Lagerung Store at 4°C
Haltbarkeit 12 months
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