GMEB1 Antikörper (Glucocorticoid Modulatory Element Binding Protein 1) (Cy5)

Details for Product anti-GMEB1 Antibody No. ABIN1704502
Antigen
  • MGC81052
  • GMEB1
  • si:ch211-245h7.5
  • pif96
  • p96pif
  • MGC147529
  • P96PIF
  • PIF96
  • 1110050A04Rik
  • AI256615
  • AI481278
  • RGD1563208
  • glucocorticoid modulatory element binding protein 1 S homeolog
  • glucocorticoid modulatory element binding protein 1
  • gmeb1.S
  • GMEB1
  • gmeb1
  • Gmeb1
Reaktivität
Human, Maus, Ratte (Rattus)
31
16
15
2
2
2
2
2
1
1
Wirt
Kaninchen
22
9
Klonalität
Polyklonal
Konjugat
Dieser GMEB1 Antikörper ist konjugiert mit Cy5
2
2
2
1
1
1
1
1
1
1
1
1
1
Applikation
Immunofluorescence (Paraffin-embedded Sections) (IF (p))
16
12
12
9
9
5
1
1
Optionen
Immunogen KLH conjugated synthetic peptide derived from human GMEB1
Isotyp IgG
Reinigung Purified by Protein A.
Plasmids, Primers & others Plasmide, Primers & weitere GMEB1 products on genomics-online (e.g. as negative or positive controls)
Antigen
Andere Bezeichnung Gmeb1 (GMEB1 Antibody Abstract)
Hintergrund

GMEB-1 is a 573 amino acid protein that contains one SAND domain and is a member of the KDWK family of combinatorial transcription modulators. Localized to both the cytoplasm and the nucleus, GMEB-1 forms a heterodimer with GMEB-2 (Glucocorticoid modulatory element-binding protein 2) and, once associated with GMEB-2, plays a key role in parvovirus DNA replication. In addition, GMEB-1 functions alone as a trans-acting factor that, by binding to glucocorticoid modulatory elements (GMEs) in TAT (tyrosine aminotransferase) promoters, increases intracellular sensitivity to glucocorticoid concentrations. GMEB-1 also interacts with initiator procaspases and, via this interaction, can inhibit caspase-induced apoptosis. Due to alternative splicing events, GMEB-1 is expressed as two isoforms.

Synonyms: DNA binding protein p96P, DNA-binding protein p96P, Glucocorticoid modulatory element binding protein 1, Glucocorticoid modulatory element-binding protein 1, GMEB 1, GMEB-1, Gmeb1, GMEB1_HUMAN, P96P, Parvovirus initiation factor p96, P 96, P p96, P96.

Gen-ID 10691
Applikations-hinweise IF(IHC-P) 1:50-200
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Lagerung 4 °C
Informationen zur Lagerung Store at 4°C
Haltbarkeit 12 months
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