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GMEB1 Antikörper (AA 301-400) (Cy5)

GMEB1 Reaktivität: Human WB, IF (cc), IF (p) Wirt: Kaninchen Polyclonal Cy5
Produktnummer ABIN1704502
  • Target Alle GMEB1 Antikörper anzeigen
    GMEB1 (Glucocorticoid Modulatory Element Binding Protein 1 (GMEB1))
    Bindungsspezifität
    • 14
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 301-400
    Reaktivität
    • 26
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human
    Wirt
    • 24
    • 2
    Kaninchen
    Klonalität
    • 24
    • 2
    Polyklonal
    Konjugat
    • 9
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser GMEB1 Antikörper ist konjugiert mit Cy5
    Applikation
    • 21
    • 12
    • 12
    • 9
    • 7
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Homologie
    Human,Mouse,Rat,Cow,Sheep,Horse,Rabbit
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human GMEB1
    Isotyp
    IgG
    Top Product
    Discover our top product GMEB1 Primärantikörper
  • Applikationshinweise
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    GMEB1 (Glucocorticoid Modulatory Element Binding Protein 1 (GMEB1))
    Andere Bezeichnung
    GMEB1 (GMEB1 Produkte)
    Synonyme
    MGC81052 antikoerper, GMEB1 antikoerper, si:ch211-245h7.5 antikoerper, pif96 antikoerper, p96pif antikoerper, MGC147529 antikoerper, P96PIF antikoerper, PIF96 antikoerper, 1110050A04Rik antikoerper, AI256615 antikoerper, AI481278 antikoerper, RGD1563208 antikoerper, glucocorticoid modulatory element binding protein 1 S homeolog antikoerper, glucocorticoid modulatory element binding protein 1 antikoerper, gmeb1.S antikoerper, GMEB1 antikoerper, gmeb1 antikoerper, Gmeb1 antikoerper
    Hintergrund

    Synonyms: DNA binding protein p96P, DNA-binding protein p96P, Glucocorticoid modulatory element binding protein 1, Glucocorticoid modulatory element-binding protein 1, GMEB 1, GMEB-1, Gmeb1, GMEB1_HUMAN, P96P, Parvovirus initiation factor p96, P 96, P p96, P96.

    Background: GMEB-1 is a 573 amino acid protein that contains one SAND domain and is a member of the KDWK family of combinatorial transcription modulators. Localized to both the cytoplasm and the nucleus, GMEB-1 forms a heterodimer with GMEB-2 (Glucocorticoid modulatory element-binding protein 2) and, once associated with GMEB-2, plays a key role in parvovirus DNA replication. In addition, GMEB-1 functions alone as a trans-acting factor that, by binding to glucocorticoid modulatory elements (GMEs) in TAT (tyrosine aminotransferase) promoters, increases intracellular sensitivity to glucocorticoid concentrations. GMEB-1 also interacts with initiator procaspases and, via this interaction, can inhibit caspase-induced apoptosis. Due to alternative splicing events, GMEB-1 is expressed as two isoforms.

    Gen-ID
    10691
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