G6PC3 Antikörper (Glucose 6-Phosphatase, Catalytic 3) (Cy5)

Details for Product anti-G6PC3 Antibody No. ABIN1704494
Antigen
  • SCN4
  • UGRP
  • 0710001K01Rik
  • AU019276
  • AU045429
  • AV128920
  • AW545836
  • glucose-6-phosphatase catalytic subunit 3
  • glucose 6 phosphatase, catalytic, 3
  • glucose 6 phosphatase catalytic subunit 3
  • G6PC3
  • G6pc3
Reaktivität
Human, Maus, Ratte (Rattus)
21
19
17
4
4
4
4
3
2
1
1
1
1
Wirt
Kaninchen
21
Klonalität
Polyklonal
Konjugat
Dieser G6PC3 Antikörper ist konjugiert mit Cy5
1
1
1
1
1
1
1
1
1
1
1
1
1
Applikation
Immunofluorescence (Paraffin-embedded Sections) (IF (p))
12
8
4
3
2
Optionen
Immunogen KLH conjugated synthetic peptide derived from human G6PC3
Isotyp IgG
Reinigung Purified by Protein A.
Plasmids, Primers & others Plasmide, Primers & weitere G6PC3 products on genomics-online (e.g. as negative or positive controls)
Antigen
Andere Bezeichnung G6pc3 (G6PC3 Antibody Abstract)
Hintergrund

Glucose-6-phosphatase (G6Pase), is a multicomponent enzyme system that hydrolyzes glucose-6-phosphate (G6P) in the final step of gluconeogenesis and gluconeolysis. G6Pase localizes to the endoplasmic reticulum, and while liver, kidney, and intestine are the only tissues that express the first identified isoform, G6Pase-Alpha, a second form, designated G6Pase-Beta, contributes to blood glucose homeostasis in a wider range of tissues. G6Pase-Beta, also known as SCN4, UGRP or G6PC3 (glucose 6 phosphatase, catalytic, 3), is a 346 amino acid endoplasmic reticulum multi-pass membrane protein that is involved in carbohydrate biosynthesis and the gluconeogenesis pathway. Inhibited by vanadate, G6Pase-Beta hydrolyzes GP6 to glucose in the endoplasmic reticulum. Due to its necessary involvement in normal glucose metabolism, G6Pase-Beta may play an integral role in diabetes and glycogen storage diseases (GSDs).

Synonyms: G-6-Pase 3, G6Pase 3, G6Pase-beta, Glucose 6 phosphatase, catalytic, 3, Glucose-6-phosphatase 3, Glucose-6-phosphatase beta, SCN4, Ubiquitous glucose-6-phosphatase catalytic subunit-related protein, UGRP,

Gen-ID 92579
Applikations-hinweise IF(IHC-P) 1:50-200
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung 4 °C
Informationen zur Lagerung Store at 4°C
Haltbarkeit 12 months
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