G6PC3 Antikörper (AA 201-300) (Cy5)

Produktnummer ABIN1704494

Der Kaninchen Polyklonal Anti-G6PC3-Antikörper wurde für WB und IF (p) validiert. Er ist geeignet, G6PC3 in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für G6PC3 Antikörper (AA 201-300) (Cy5) (ABIN1704494)

Target: G6PC3 (Glucose 6-Phosphatase, Catalytic 3 (G6PC3))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser G6PC3 Antikörper ist konjugiert mit Cy5

Applikation: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-G6PC3 Antikörper (Cy5)

Bindungsspezifität: AA 201-300

Kreuzreaktivität: Human, Maus, Ratte

Homologie: Cow,Sheep,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human G6PC3

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu G6PC3

Target: G6PC3 (Glucose 6-Phosphatase, Catalytic 3 (G6PC3))

Andere Bezeichnung: G6PC3

Hintergrund:

Synonyms: G-6-Pase 3, G6Pase 3, G6Pase-beta, Glucose 6 phosphatase, catalytic, 3, Glucose-6-phosphatase 3, Glucose-6-phosphatase beta, SCN4, Ubiquitous glucose-6-phosphatase catalytic subunit-related protein, UGRP,

Background: Glucose-6-phosphatase (G6Pase), is a multicomponent enzyme system that hydrolyzes glucose-6-phosphate (G6P) in the final step of gluconeogenesis and gluconeolysis. G6Pase localizes to the endoplasmic reticulum, and while liver, kidney, and intestine are the only tissues that express the first identified isoform, G6Pase-Alpha, a second form, designated G6Pase-Beta, contributes to blood glucose homeostasis in a wider range of tissues. G6Pase-Beta, also known as SCN4, UGRP or G6PC3 (glucose 6 phosphatase, catalytic, 3), is a 346 amino acid endoplasmic reticulum multi-pass membrane protein that is involved in carbohydrate biosynthesis and the gluconeogenesis pathway. Inhibited by vanadate, G6Pase-Beta hydrolyzes GP6 to glucose in the endoplasmic reticulum. Due to its necessary involvement in normal glucose metabolism, G6Pase-Beta may play an integral role in diabetes and glycogen storage diseases (GSDs).

Gen-ID: 92579

UniProt: Q9BUM1