FAM134B Antikörper (AA 210-310) (Cy5)
Kurzübersicht für FAM134B Antikörper (AA 210-310) (Cy5) (ABIN1704485)
Target
Alle FAM134B Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 210-310
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Spezifität
- There is a chance that this protein will cross-react with MSL2 based on a 73 % non-sequential sequence similarity.
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Kreuzreaktivität
- Human, Maus, Ratte
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Homologie
- Cow,Rabbit
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Aufreinigung
- Purified by Protein A.
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Immunogen
- KLH conjugated synthetic peptide derived from human FAM134B
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Isotyp
- IgG
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Applikationshinweise
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FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 μg/μL
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Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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Haltbarkeit
- 12 months
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- FAM134B (Family with Sequence Similarity 134, Member B (FAM134B))
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Andere Bezeichnung
- FAM134B
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Hintergrund
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Synonyms: JK1, JK-1, Reticulophagy receptor FAM134B, FAM134B
Background: Endoplasmic reticulum-anchored autophagy receptor that mediates ER delivery into lysosomes through sequestration into autophagosomes (PubMed:26040720). Promotes membrane remodeling and ER scission via its membrane bending capacity and targets the fragments into autophagosomes via interaction with ATG8 family proteins (PubMed:26040720). Required for long-term survival of nociceptive and autonomic ganglion neurons (PubMed:19838196, PubMed:26040720).
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Gen-ID
- 54463
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UniProt
- Q9H6L5
Target
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