DRAXIN Antikörper (Dorsal Inhibitory Axon Guidance Protein) (Cy5)

Details for Product anti-DRAXIN Antibody No. ABIN1704416
Antigen
  • C1orf187
  • draxin
  • AGPA3119
  • UNQ3119
  • neucrin
  • 2610109H07Rik
  • MGC113312
  • dorsal inhibitory axon guidance protein
  • DRAXIN
  • Draxin
  • draxin
Reaktivität
Human, Maus, Ratte (Rattus)
47
42
39
4
3
3
1
1
1
Wirt
Kaninchen
46
5
Klonalität
Polyklonal
Konjugat
Dieser DRAXIN Antikörper ist konjugiert mit Cy5
3
3
2
2
2
2
2
2
2
2
2
2
2
1
Applikation
Immunofluorescence (Paraffin-embedded Sections) (IF (p))
28
25
15
10
7
4
4
1
1
Optionen
Immunogen KLH conjugated synthetic peptide derived from human C1orf187
Isotyp IgG
Reinigung Purified by Protein A.
Plasmids, Primers & others Plasmide, Primers & weitere DRAXIN products on genomics-online (e.g. as negative or positive controls)
Antigen
Andere Bezeichnung C1orf187 (DRAXIN Antibody Abstract)
Hintergrund

C1orf187, also known as Draxin, Dorsal repulsive axon guidance protein and Neucrin, is a 349 amino acid secreted protein that is required of the development of the spinal cord and forebrain commissures. C1orf187 acts as a chemorepulsive guidance protein and directs commissural axons during development by repelling neurite outgrowth from the spinal cord. During development, C1orf187 modulates neural crest migration by reducing the polarization of these cells, leading to reduced velocity of migration and increased frequency of changing direction, leading to a net decrease in migrational distance. It acts as an antagonist of the Wnt signaling pathway by inhibiting the stabilization of cytosolic i²-catenin via its interaction with LRP6. C1orf187 inhibits outgrowth from the olfactory bulb and likely contributes to the formation of the lateral olfactory tract.

Synonyms: AGPA3119, C1orf187, Chromosome 1 open reading frame 187, Dorsal inhibitory axon guidance protein, Dorsal repulsive axon guidance protein, DRAXI_HUMAN, Draxin, FLJ34999, MGC117222, Neucrin, OTTHUMP00000002262, UNQ3119.

Gen-ID 374946
Applikations-hinweise IF(IHC-P) 1:50-200
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Lagerung 4 °C
Informationen zur Lagerung Store at 4°C
Haltbarkeit 12 months
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