CAPRIN2 Antikörper (AA 101-200) (Cy5)
Kurzübersicht für CAPRIN2 Antikörper (AA 101-200) (Cy5) (ABIN1704401)
Target
Alle CAPRIN2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 101-200
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Kreuzreaktivität
- Human, Maus, Ratte
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Homologie
- Sheep,Pig,Horse,Chicken
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Aufreinigung
- Purified by Protein A.
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Immunogen
- KLH conjugated synthetic peptide derived from human CAPRIN2
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Isotyp
- IgG
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Applikationshinweise
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 μg/μL
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Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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Haltbarkeit
- 12 months
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- CAPRIN2 (Caprin Family Member 2 (CAPRIN2))
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Andere Bezeichnung
- CAPRIN2
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Hintergrund
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Synonyms: C1q domain-containing protein 1, C1QDC1, CAPR2_HUMAN, Caprin family member 2, Caprin-2, caprin2, Cytoplasmic activation/proliferation-associated protein 2, EEG 1, EEG1, Gastric cancer multidrug resistance-associated protein, KIAA1873, Protein EEG-1, RNA granule protein 140, RNG140.
Background: Caprin2 is 1127 amino acid highly conserved protein that is ubiquitously expressed with highest levels of expression in brain and spleen. Caprin2 stabilizes cytosolic _-catenin and enhances LEF-1 dependent reporter gene activity as well as the expression of Wnt target genes in mammalian cells. Caprin2 promotes LRP5/6 phosphorylation by GSK-3 and enhances the interaction between Axin and LRP5/6. It is suggested that Caprin2 functions as a proapoptotic inhibitor of the cell cycle. Nine isoforms of Caprin2 exist due to alternative splicing events.
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Gen-ID
- 65981
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UniProt
- Q6IMN6
Target
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