GATA3 Antikörper (GATA Binding Protein 3) (pSer162) (Cy5)

Details for Product anti-GATA3 Antibody No. ABIN1704397
Antigen
  • HDR
  • HDRS
  • Gata-3
  • jal
  • cb550
  • gta3
  • GATA-3
  • XGATA3
  • xgata-3
  • hdr
  • xGATA-3
  • GATA3
  • GATA transcription factor 3
  • T4L20.260
  • T4L20_260
  • gata3
  • GATA binding protein 3
  • GATA binding protein 3 S homeolog
  • GATA transcription factor 3
  • amidase
  • putative amidase
  • GATA-binding protein 3
  • GATA3
  • Gata3
  • gata3
  • gata3.S
  • gatA3
Epitop
pSer162
43
17
15
14
11
10
9
9
8
8
8
7
6
6
3
3
3
2
2
1
1
1
1
1
1
1
Reaktivität
Human, Maus, Ratte (Rattus)
239
128
53
15
13
10
8
7
7
5
5
4
4
2
1
Wirt
Kaninchen
153
65
21
8
Klonalität
Polyklonal
Konjugat
Dieser GATA3 Antikörper ist konjugiert mit Cy5
11
6
6
6
6
6
6
5
5
4
3
3
2
2
2
2
2
Applikation
Immunofluorescence (Paraffin-embedded Sections) (IF (p))
164
94
64
45
37
26
12
8
8
6
3
2
1
1
Optionen
Immunogen KLH conjugated synthetic phosphopeptide derived from human GATA3 around the phosphorylation site of Ser162
Isotyp IgG
Reinigung Purified by Protein A.
Plasmids, Primers & others Plasmide, Primers & weitere GATA3 products on genomics-online (e.g. as negative or positive controls)
Antigen
Andere Bezeichnung GATA3 (GATA3 Antibody Abstract)
Hintergrund

Members of the GATA family share a conserved zinc finger DNA-binding domain and are capable of binding the WGATAR consensus sequence. GATA-1 is erythroid-specific and is responsible for the regulated transcription of erythroid genes. It is an essential component in the generation of the erythroid lineage. GATA-2 is expressed in embryonic brain and liver, HeLa and endothelial cells, as well as in erythroid cells. Studies with a modified GATA consensus sequence, AGATCTTA, have shown that GATA-2 and GATA-3 recognize this mutated consensus while GATA-1 has poor recognition of this sequence. This indicates broader regulatory capabilities of GATA-2 and GATA-3 than GATA-1. GATA-3 is highly expressed in T lymphocytes. GATA-4, GATA-5 and GATA-6 comprise a subfamily of transcription factors. Both GATA-4 and GATA-6 are found in heart, pancreas and ovary, lung and liver tissues exhibit GATA-6, but not GATA-4 expression. GATA-5 expression has been observed in differentiated heart and gut tissues and is present throughout the course of development in the heart. Although expression patterns of the various GATA transcription factors may overlap, it is not yet apparent how the GATA factors are able to discriminate in binding their appropriate target sites.

Subcellular location: Extracellular, Helical

Synonyms: GATA3 phospho S162, p-GATA3 phospho S162, GATA3 phospho Ser162, p-GATA3 Ser162, GATA 3, GATA3, GATA-3, GATA binding factor 3, GATA binding protein 3, HDR, MGC2346, MGC5199, MGC5445, Trans acting T cell specic transcription factor GATA 3, GATA3_HUMAN, Trans-acting T-cell-specic transcription factor GATA-3, GATA-binding factor 3.

Gen-ID 2625
Pathways Hormone Transport, Regulation of Hormone Metabolic Process, Tube Formation
Applikations-hinweise IF(IHC-P) 1:50-200
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Lagerung 4 °C
Informationen zur Lagerung Store at 4°C
Haltbarkeit 12 months
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