Supervillin (SVIL) Antikörper (Cy5)

Details zu Produkt Nr. ABIN1704357
Antigen
  • sb:cb867
  • svil
  • wu:fd05a09
  • SVIL
  • DKFZp468F0819
  • AU024053
  • B430302E16Rik
  • supervillin a
  • supervillin
  • supervillin, putative
  • svila
  • SVIL
  • LOC5577073
  • CpipJ_CPIJ003700
  • Smp_148580
  • svil
  • Svil
Reaktivität
Human, Maus, Ratte (Rattus)
37
15
14
Wirt
Kaninchen
29
7
1
Klonalität
Polyklonal
Konjugat
Cy5
5
5
1
1
1
1
1
1
1
1
1
1
1
Applikation
Immunofluorescence (Paraffin-embedded Sections) (IF (p))
23
12
9
7
5
4
4
4
3
1
Optionen
Immunogen KLH conjugated synthetic peptide derived from human Supervillin
Isotyp IgG
Reinigung Purified by Protein A.
Antigen
Andere Bezeichnung Supervillin (SVIL Antibody Abstract)
Hintergrund

Forms a high-affinity link between the actin cytoskeleton and the membrane. Isoform 1 (archvillin) is among the first costameric proteins to assemble during myogenesis and it contributes to myogenic membrane structure and differentiation. Appears to be involved in myosin II assembly. May modulate myosin II regulation through MLCK during cell spreading, an initial step in cell migration. May play a role in invadopodial function. Isoform 2 may be involved in modulation of focal adhesions. Supervillin-mediated down-regulation of focal adhesions involves binding to TRIP6. Plays a role in cytokinesis through KIF14 interaction (By similarity).

Subcellular location: Cell membrane

Synonyms: Supervillin, Archvillin, p205/p250, SVIL

Gen-ID 6840
UniProt O95425
Applikations-hinweise IF(IHC-P) 1:50-200
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Lagerung 4 °C
Informationen zur Lagerung Store at 4°C
Haltbarkeit 12 months
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