SNX5 Antikörper (Sorting Nexin 5) (Cy5)

Details for Product anti-SNX5 Antibody No. ABIN1704354
Antigen
  • 0910001N05Rik
  • 1810032P22Rik
  • AU019504
  • D2Ertd52e
  • id:ibd5091
  • wu:fa66c10
  • wu:fi28h04
  • zgc:55769
  • SNX5
  • snx5
  • sorting nexin 5
  • sorting nexin 5 S homeolog
  • SNX5
  • Snx5
  • snx5.S
  • snx5
Reaktivität
Human, Maus, Ratte (Rattus)
69
44
42
9
8
7
5
4
4
3
3
2
1
Wirt
Kaninchen
50
20
Klonalität
Polyklonal
Konjugat
Dieser SNX5 Antikörper ist konjugiert mit Cy5
6
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
Applikation
Immunofluorescence (Paraffin-embedded Sections) (IF (p))
51
29
19
12
4
2
Optionen
Immunogen KLH conjugated synthetic peptide derived from human SNX5
Isotyp IgG
Reinigung Purified by Protein A.
Plasmids, Primers & others Plasmide, Primers & weitere SNX5 products on genomics-online (e.g. as negative or positive controls)
Antigen
Andere Bezeichnung Snx5 (SNX5 Antibody Abstract)
Hintergrund

Sorting nexin 1 (SNX1) is a member of a large family of hydrophilic proteins that interact with a variety of receptor types and are involved in intracellular trafficking (1). SNX1 and the related splice variant, SNX1A, bind the epidermal growth factor (EGF) receptor, facilitate its transport to lysosome, and thereby contribute to the degradation of the receptor (2,3). SNX2 and SNX4 share a high degree of amino acid similarity with SNX1, as they all contain a characteristic phox homology (PX) domain (4). These proteins are all partially associated with cellular membranes, and they, likewise, associate with EGF, PDGF and insulin receptor tyrosine kinases (2). These nexins are widely expressed and yet have various tissue distribution patterns. Additionally, the sorting nexins can associate with each other and with a variety of other cellular proteins, suggesting that they exist as part of multisubunit complexes (1,5). The related protein, SNX3, comprises a distinct subgroup of nexins that share less sequence similarity outside of the PX domain and have dramatically different binding affinities for the tyrosine kinase receptors (2,6).

Synonyms: 0910001N05Rik, 1810032P22Rik, AU019504, D2Ertd52e, FLJ10931, OTTHUMP00000030340, OTTHUMP00000062927, OTTMUSP00000003367, OTTMUSP00000003368, RP11-504H3.2, RP23-35E16.2, snoRNA MBI-43, SNX 5, SNX5, SNX5_HUMAN, Sorting nexin 5, Sorting nexin-5.

Gen-ID 27131
Applikations-hinweise IF(IHC-P) 1:50-200
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Lagerung 4 °C
Informationen zur Lagerung Store at 4°C
Haltbarkeit 12 months