PUM2 Antikörper (AA 901-1066) (Cy5)

Produktnummer ABIN1704346

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch PUM2 in WB, IF (cc) und IF (p). Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für PUM2 Antikörper (AA 901-1066) (Cy5) (ABIN1704346)

Target: PUM2 (Pumilio Homolog 2 (Drosophila) (PUM2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PUM2 Antikörper ist konjugiert mit Cy5

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-PUM2 Antikörper (Cy5)

Bindungsspezifität: AA 901-1066

Homologie: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Pumilio 2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu PUM2

Target: PUM2 (Pumilio Homolog 2 (Drosophila) (PUM2))

Andere Bezeichnung: Pumilio 2

Hintergrund:

Synonyms: FLJ36528, KIAA0235, MGC138251, MGC138253, PUM 2, Pum2, PUM2, PUMH2, Pumilio Drosphila homolog 2, Pumilio homolog 2 Drosophila, Pumilio homolog 2, Pumilio2, PUM2_HUMAN.

Background: Pumilio 2 is a sequence-specific RNA-binding protein that regulates translation and mRNA stability by binding mRNA targets. It supports proliferation and self-renewal of stem cells by regulating the translation of key transcripts. The Pumilio gene encodes proteins that are required for development of germ stem cells in one or both sexes. The Pumilio protein interacts with the human Nanos1 protein and this interaction may play a conserved role in germ cell development. Pumilio 2 is highly expressed in testis and ovary and at lower levels in brain, heart, kidney, liver, muscle, placenta, intestine and stomach. It is also expressed in stem cells, germ cells and in most fetal tissues.

Gen-ID: 23369

Pathways: Ribonucleoprotein Complex Subunit Organization