Patched Domain Containing 2 (PTCHD2) Antikörper (Cy5)

Details zu Produkt Nr. ABIN1704345
Antigen
  • DISP3
  • G630052C06Rik
  • RNDEu-2
  • RGD1305820
  • dispatched RND transporter family member 3
  • patched domain-containing protein 2
  • si:dkey-32e23.6
  • DISP3
  • LOC100082708
  • si:dkey-32e23.6
  • disp3
  • Disp3
Reaktivität
Human, Maus, Ratte (Rattus)
48
19
19
Wirt
Kaninchen
48
Klonalität
Polyklonal
Konjugat
Cy5
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
Applikation
Immunofluorescence (Paraffin-embedded Sections) (IF (p))
22
19
17
12
10
3
1
1
Optionen
Immunogen KLH conjugated synthetic peptide derived from human PTCHD2/DISP3
Isotyp IgG
Reinigung Purified by Protein A.
Antigen
Andere Bezeichnung Ptchd2/Disp3
Hintergrund

PTCHD2 is a 1,392 amino acid multi-pass membrane protein that contains one SSD (sterol-sensing) domain and belongs to the patched family. Expressed in retina, brain and testis, PTCHD2 localizes to endoplasmic reticulum and colocalizes with cholesterol. PTCHD2 overexpression leads to increased cholesterol levels, suggesting that PTCHD2 may play a role in cholesterol homeostasis. PTCHD2 is further hypothesized to act as a link between thyroid hormone and cholesterol metabolism. Existing as two alternatively spliced isoforms, PTCHD2 is thought to assist in the release of lipid-anchored secreted proteins and is encoded by a gene that maps to human chromosome 1p36.22.

Subcellular location: Extracellular

Synonyms: DISP3, Dispatched, drosophila, homolog of, 3, G630052C06Rik, hCG_24779, KIAA1337, Patched domain-containing protein 2, Protein dispatched homolog 3, Ptchd2, PTHD2_HUMAN, RGD1305820, RND-type protein RNDEu-2, RNDEu-2, patched domain containing 2, RP23-157B15.1.

Gen-ID 57540
Applikations-hinweise IF(IHC-P) 1:50-200
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Lagerung 4 °C
Informationen zur Lagerung Store at 4°C
Haltbarkeit 12 months
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