EPRS Antikörper (Glutamyl-Prolyl-tRNA Synthetase) (Cy5)

Details for Product anti-EPRS Antibody No. ABIN1704312
Antigen
  • EARS
  • GLUPRORS
  • PARS
  • QARS
  • QPRS
  • wu:fb38d08
  • wu:ft34d10
  • 2410081F06Rik
  • 3010002K18Rik
  • C79379
  • Qprs
  • glutamyl-prolyl-tRNA synthetase
  • glutamyl-prolyl-tRNA synthetase S homeolog
  • EPRS
  • eprs
  • eprs.S
  • Eprs
Reaktivität
Human, Maus, Ratte (Rattus)
68
44
25
4
4
3
2
2
2
2
1
1
1
Wirt
Kaninchen
70
Klonalität
Polyklonal
Konjugat
Dieser EPRS Antikörper ist konjugiert mit Cy5
5
4
4
4
4
4
3
2
2
1
1
1
1
1
Applikation
Immunofluorescence (Paraffin-embedded Sections) (IF (p))
34
14
12
11
7
5
3
2
2
1
Optionen
Immunogen KLH conjugated synthetic peptide derived from human Glutamyl Prolyl tRNA syntase/ProRS
Isotyp IgG
Reinigung Purified by Protein A.
Plasmids, Primers & others Plasmide, Primers & weitere EPRS products on genomics-online (e.g. as negative or positive controls)
Antigen
Andere Bezeichnung Glutamyl Prolyl Trna Synthetase/Prors (EPRS Antibody Abstract)
Hintergrund

Catalyzes the attachment of the cognate amino acid to the corresponding tRNA in a two-step reaction: the amino acid is first activated by ATP to form a covalent intermediate with AMP and is then transferred to the acceptor end of the cognate tRNA. Component of the GAIT (gamma interferon-activated inhibitor of translation) complex which mediates interferon-gamma-induced transcript-selective translation inhibition in inflammation processes. Upon interferon-gamma activation and subsequent phosphorylation dissociates from the multisynthetase complex and assembles into the GAIT complex which binds to stem loop-containing GAIT elements in the 3'-UTR of diverse inflammatory mRNAs (such as ceruplasmin) and suppresses their translation.

Subcellular location: Cytoplasm

Synonyms: EARS, PARS, QARS, QPRS, PIG32, GLUPRORS, Bifunctional glutamate/proline--tRNA ligase, Bifunctional aminoacyl-tRNA synthetase, Cell proliferation-inducing gene 32 protein, Glutamatyl-prolyl-tRNA synthetase, EPRS, GLNS

Gen-ID 2058
UniProt P07814
Applikations-hinweise IF(IHC-P) 1:50-200
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Lagerung 4 °C
Informationen zur Lagerung Store at 4°C
Haltbarkeit 12 months
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