FZD10 Antikörper (Frizzled Family Receptor 10) (AA 100-150) (Cy5)

Details for Product anti-FZD10 Antibody No. ABIN1704288
Antigen
  • CD350
  • FZ-10
  • Fz10
  • FzE7
  • hFz10
  • cFz-10
  • Fz-10
  • Xfr9
  • Xfz10
  • frizzled-10
  • frizzled10
  • fz10
  • fze7
  • hfz10
  • fk48e04
  • fz4
  • fzb
  • wu:fk48e04
  • zg04
  • Xfz10B
  • Xfz9
  • fzd10b
  • fzd9
  • frizzled class receptor 10
  • frizzled class receptor 10 S homeolog
  • FZD10
  • fzd10
  • Fzd10
  • fzd10.S
Epitop
AA 100-150
14
9
5
4
4
3
2
1
1
1
1
1
1
Reaktivität
Human, Maus, Ratte (Rattus)
70
59
22
9
4
4
4
3
2
1
Wirt
Kaninchen
78
Klonalität
Polyklonal
Konjugat
Dieser FZD10 Antikörper ist konjugiert mit Cy5
4
3
2
2
2
2
2
2
1
1
1
1
1
1
Applikation
Immunofluorescence (Paraffin-embedded Sections) (IF (p))
46
29
14
13
12
10
3
3
1
1
Optionen
Immunogen KLH conjugated synthetic peptide derived from human Frizzled 10/CD350
Isotyp IgG
Spezifität Due to the similarity of this protein to Frizzled 9, there is a chance that this antibody will react with this protein based on homology.
Reinigung Purified by Protein A.
Plasmids, Primers & others Plasmide, Primers & weitere FZD10 products on genomics-online (e.g. as negative or positive controls)
Antigen
Andere Bezeichnung Frizzled 10/CD350 (FZD10 Antibody Abstract)
Hintergrund

Receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to involve interactions with G-proteins. May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues.

Subcellular location: Extracellular

Synonyms: Fz10, FzE7, CD350, FZ-10, hFz10, Frizzled-10, FZD10

Gen-ID 11211
UniProt Q9ULW2
Pathways WNT Signalweg
Applikations-hinweise IF(IHC-P) 1:50-200
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Lagerung 4 °C
Informationen zur Lagerung Store at 4°C
Haltbarkeit 12 months
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