POLL Antikörper (Polymerase (DNA Directed), lambda) (Cy5)

Details for Product anti-POLL Antibody No. ABIN1704266
Antigen
  • T10O24.13
  • T10O24_13
  • zgc:66320
  • zgc:77901
  • wu:fe49a04
  • beta-n
  • pol-kappa
  • BETAN
  • POLKAPPA
  • 1110003P06Rik
  • AV007317
  • DNA polymerase lambda (POLL)
  • DNA polymerase lambda
  • polymerase (DNA directed), lambda
  • polymerase (DNA) lambda
  • Pol{lambda}
  • PTRG_00468
  • poll
  • POLL
  • MCYG_03796
  • LOC9325878
  • MGYG_02138
  • Poll
Reaktivität
Human, Maus, Ratte (Rattus)
82
45
33
7
6
5
4
4
2
2
2
2
2
1
Wirt
Kaninchen
61
21
Klonalität
Polyklonal
Konjugat
Dieser POLL Antikörper ist konjugiert mit Cy5
4
3
3
2
2
2
2
2
1
1
1
1
1
1
1
1
1
Applikation
Immunofluorescence (Paraffin-embedded Sections) (IF (p))
44
37
17
12
11
3
2
2
1
1
Optionen
Immunogen KLH conjugated synthetic peptide derived from human DNA Polymerase lambda
Isotyp IgG
Reinigung Purified by Protein A.
Plasmids, Primers & others Plasmide, Primers & weitere POLL products on genomics-online (e.g. as negative or positive controls)
Antigen
Andere Bezeichnung Dna Polymerase lambda (POLL Antibody Abstract)
Hintergrund

DNA polymerase lambda (pol lambda), also designated DNA polymerase lambda or Pol Beta2, is a low-fidelity polymerase which plays a role in both spontaneous and DNA damage-induced mutagenesis. Encoded by the POLL gene, pol lambda is a member of the DNA polymerase type-X family. Pol lambda extends primer-terminal mispairs opposite nondamaged DNA templates, suggesting that it may assist in extending mismatched base pairs during normal DNA replication. In addition, pol ?may play a role in the mutagenic bypass of T-T dimers. Proliferating cell nuclear antigen (PCNA), a protein essential to DNA replication, interacts with pol lambda and thus influences the ability of pol ?to synthesize DNA.

Synonyms: BETA N, BETAN, DNA directed DNA polymerase lambda, DNA polymerase beta 2, DNA polymerase beta-2, DNA polymerase kappa, DNA polymerase kappa DNA polymerase beta N, DNA polymerase lambda, DNA polymerase lamda2, DPOLL_HUMAN, EC 2.7.7.7,EC 4.2.99., FLJ46002, OTTHUMP00000020321, OTTHUMP00000020323, OTTHUMP00000059179, Pol beta2, POL KAPPA, Pol Lambda, POLKAPPA, POLL, Polymerase DNA directed lambda.

Gen-ID 27343
Pathways DNA Reparatur, Production of Molecular Mediator of Immune Response
Applikations-hinweise IF(IHC-P) 1:50-200
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Lagerung 4 °C
Informationen zur Lagerung Store at 4°C
Haltbarkeit 12 months
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