Chromosome 1 Open Reading Frame 55 (C1orf55) Antikörper (Cy5)

Details zu Produkt Nr. ABIN1704245
Antigen
  • C1orf55
  • RP4-671D7.1
  • dJ671D7.1
  • SDE2
  • c1orf55
  • DKFZp469F1217
  • RGD1305572
  • wu:fb55e02
  • wu:fi34c02
  • zgc:112095
  • SDE2 telomere maintenance homolog
  • SDE2 telomere maintenance homolog (S. pombe) S homeolog
  • SDE2 telomere maintenance homolog (S. pombe)
  • SDE2
  • sde2.S
  • sde2
  • Sde2
Reaktivität
Human, Maus, Ratte (Rattus)
27
18
18
3
2
2
2
2
2
1
1
1
1
Wirt
Kaninchen
27
Klonalität
Polyklonal
Konjugat
Cy5
1
1
1
1
1
1
1
1
1
1
1
1
1
Applikation
Immunofluorescence (Paraffin-embedded Sections) (IF (p))
12
10
8
2
2
2
1
Optionen
Immunogen KLH conjugated synthetic peptide derived from human C1orf55
Isotyp IgG
Reinigung Purified by Protein A.
Antigen
Andere Bezeichnung C1orf55
Hintergrund

Belonging to the UPF0667 family, C1orf55 is a 451 amino acid protein that is phosphorylated upon DNA damage, likely by Atm or ATR. There are three different isoforms of C1orf55 that are produced as a result of alternative splicing events. The gene encoding C1orf55 maps to human chromosome 1, the largest human chromosome spanning about 260 million base pairs and making up 8 % of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1.

Synonyms: C1orf55, CA055_HUMAN, Chromosome 1 open reading frame 55, dJ671D7.1, FLJ35382, Hypothetical protein LOC163859, RP4 671D7.1, UPF0667 protein C1orf55.

Gen-ID 163859
Applikations-hinweise IF(IHC-P) 1:50-200
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Lagerung 4 °C
Informationen zur Lagerung Store at 4°C
Haltbarkeit 12 months
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