Chromosome 1 Open Reading Frame 43 (C1orf43) Antikörper (Cy5)

Details zu Produkt Nr. ABIN1704244
Antigen
  • NICE-3
  • NS5ATP4
  • S863-3
  • c1orf43
  • chromosome 1 open reading frame 43
  • chromosome 1 open reading frame 43 L homeolog
  • C1orf43
  • c1orf43.L
Reaktivität
Human, Maus, Ratte (Rattus)
19
16
16
2
2
2
2
2
2
1
1
Wirt
Kaninchen
19
Klonalität
Polyklonal
Konjugat
Cy5
1
1
1
1
1
1
1
1
1
1
1
1
1
Applikation
Immunofluorescence (Paraffin-embedded Sections) (IF (p))
12
7
4
Optionen
Immunogen KLH conjugated synthetic peptide derived from human C1orf43
Isotyp IgG
Reinigung Purified by Protein A.
Antigen
Andere Bezeichnung C1orf43
Hintergrund

C1orf43, also known as Hepatitis C virus NS5A-transactivated protein 4 and Protein NICE-3, is a 253 amino acid single-pass membrane protein. There are five isoforms of C1orf43 that are produced as a result of alternative splicing events. The gene encoding C1orf43 maps to human chromosome 1, the largest human chromosome spanning about 260 million base pairs and making up 8 % of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1.

Synonyms: 4933434E20Rik, AI462154, C1orf43, CA043_HUMAN, Chromosome 1 open reading frame 43, HCV NS5A transactivated protein 4, HCV NS5A-transactivated protein 4, Hepatitis C virus NS5A transactivated protein 4, Hepatitis C virus NS5A-transactivated protein 4, HSPC012, Hypothetical protein LOC25912, MGC111001, NICE 3, NICE3, NS5ATP4, OTTHUMP00000034199, OTTHUMP00000034201, OTTHUMP00000034202, Protein NICE 3, Protein NICE-3, Riken cDNA 4933434E20, S863 3, S863-3, Uncharacterized protein C1orf43.

Gen-ID 25912
Applikations-hinweise IF(IHC-P) 1:50-200
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Lagerung 4 °C
Informationen zur Lagerung Store at 4°C
Haltbarkeit 12 months
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