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C1orf43 Antikörper (AA 11-100) (Cy5)

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch C1orf43 in WB, IF (cc) und IF (p). Er zeigt eine Reaktivität gegenüber Human.
Produktnummer ABIN1704244

Kurzübersicht für C1orf43 Antikörper (AA 11-100) (Cy5) (ABIN1704244)

Target

C1orf43 (Chromosome 1 Open Reading Frame 43 (C1orf43))

Reaktivität

  • 17
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
Human

Wirt

  • 17
Kaninchen

Klonalität

  • 17
Polyklonal

Konjugat

  • 4
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser C1orf43 Antikörper ist konjugiert mit Cy5

Applikation

  • 17
  • 12
  • 12
  • 3
  • 3
  • 3
  • 1
Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • Bindungsspezifität

    • 14
    • 1
    • 1
    • 1
    AA 11-100

    Kreuzreaktivität

    Human

    Homologie

    Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit

    Aufreinigung

    Purified by Protein A.

    Immunogen

    KLH conjugated synthetic peptide derived from human C1orf43

    Isotyp

    IgG
  • Applikationshinweise

    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 μg/μL

    Buffer

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    Konservierungsmittel

    ProClin

    Vorsichtsmaßnahmen

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    Haltbarkeit

    12 months
  • Target

    C1orf43 (Chromosome 1 Open Reading Frame 43 (C1orf43))

    Andere Bezeichnung

    C1orf43

    Hintergrund

    Synonyms: 4933434E20Rik, AI462154, C1orf43, CA043_HUMAN, Chromosome 1 open reading frame 43, HCV NS5A transactivated protein 4, HCV NS5A-transactivated protein 4, Hepatitis C virus NS5A transactivated protein 4, Hepatitis C virus NS5A-transactivated protein 4, HSPC012, Hypothetical protein LOC25912, MGC111001, NICE 3, NICE3, NS5ATP4, OTTHUMP00000034199, OTTHUMP00000034201, OTTHUMP00000034202, Protein NICE 3, Protein NICE-3, Riken cDNA 4933434E20, S863 3, S863-3, Uncharacterized protein C1orf43.

    Background: C1orf43, also known as Hepatitis C virus NS5A-transactivated protein 4 and Protein NICE-3, is a 253 amino acid single-pass membrane protein. There are five isoforms of C1orf43 that are produced as a result of alternative splicing events. The gene encoding C1orf43 maps to human chromosome 1, the largest human chromosome spanning about 260 million base pairs and making up 8 % of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1.

    Gen-ID

    25912
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