BMP-8 Antikörper (Cy5)

Details zu Produkt Nr. ABIN1704237
Antigen
  • BMP8
  • OP2
  • Op3
  • bone morphogenetic protein 8b
  • bone morphogenetic protein 8B
  • BMP8B
  • Bmp8b
  • LOC607768
Reaktivität
Human, Maus, Ratte (Rattus)
73
26
20
2
2
2
1
1
1
1
1
Wirt
Kaninchen
65
10
3
Klonalität
Polyklonal
Konjugat
Cy5
4
3
3
3
3
3
2
2
1
1
1
1
1
1
Applikation
Immunofluorescence (Paraffin-embedded Sections) (IF (p))
42
25
14
13
10
3
3
2
2
2
Optionen
Immunogen KLH conjugated synthetic peptide derived from human BMP8b
Isotyp IgG
Reinigung Purified by Protein A.
Antigen
Andere Bezeichnung Bmp8b
Hintergrund

Bone morphogenic proteins (BMPs) are members of the TGF Beta superfamily. BMPs are involved in the induction of cartilage and bone formation. In vivo studies have shown that BMP-2 (also designated BMP-2A) and BMP-3 can independently induce cartilage formation. Smad3 association with the TGF Beta receptor complex and Smad1 translocation to the nucleus are observed after the addition of BMP-4 (also designated BMP-2B), suggesting that BMP-4 may play a role in activation of the Smad pathway. BMP-5, BMP-6 and BMP-7 all share high sequence homology with BMP-2, indicating that they each may be able to induce cartilage formation. BMP-8 (also designated OP-2) is thought to be involved in early development, as detectable expression has not been found in adult organs.

Synonyms: BMP-8, BMP-8B, BMP8, Bmp8b, BMP8B_HUMAN, Bone morphogenetic protein 8, Bone morphogenetic protein 8B, OP-2, OP2, Osteogenic protein 2.

Gen-ID 656
Applikations-hinweise IF(IHC-P) 1:50-200
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Lagerung 4 °C
Informationen zur Lagerung Store at 4°C
Haltbarkeit 12 months
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