ATP6V1B2 Antikörper (ATPase, H+ Transporting, Lysosomal 56/58kDa, V1 Subunit B2) (Cy5)

Details for Product anti-ATP6V1B2 Antibody No. ABIN1704233
Antigen
  • Atp6b1b2
  • Atp6b2
  • Vatb
  • vha55
  • VATB
  • ATP6B1B2
  • ATP6B2
  • HO57
  • VPP3
  • Vma2
  • atp6v1bb
  • fj51e01
  • vatB2
  • wu:fj51e01
  • zgc:109771
  • AI194269
  • AI790362
  • R74844
  • ATPase H+ transporting V1 subunit B2
  • ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2 S homeolog
  • ATPase, H+ transporting, lysosomal, V1 subunit B2
  • ATPase, H+ transporting, lysosomal V1 subunit B2
  • Atp6v1b2
  • atp6v1b2.S
  • ATP6V1B2
  • atp6v1b2
Reaktivität
Human, Maus, Ratte (Rattus)
58
37
36
5
4
4
3
3
3
2
2
2
1
1
Wirt
Kaninchen
44
15
Klonalität
Polyklonal
Konjugat
Dieser ATP6V1B2 Antikörper ist konjugiert mit Cy5
2
2
2
2
1
1
1
1
1
1
1
1
1
Applikation
Immunofluorescence (Paraffin-embedded Sections) (IF (p))
41
17
13
9
7
2
1
Optionen
Immunogen KLH conjugated synthetic peptide derived from human ATP6V1B2/V-ATPase B2
Isotyp IgG
Reinigung Purified by Protein A.
Antigen
Andere Bezeichnung ATP6V1B2/V-ATPase B2 (ATP6V1B2 Antibody Abstract)
Hintergrund

Vacuolar-type H+-ATPase (V-ATPase) is a multisubunit enzyme responsible for acidification of eukaryotic intracellular organelles. V-ATPases pump protons against an electrochemical gradient, while F-ATPases reverse the process, thereby synthesizing ATP. A peripheral V1 domain, which is responsible for ATP hydrolysis, and a integral V0 domain, which is responsible for proton translocation, compose V-ATPase. Nine subunits (Aâ€"H) make up the V1 domain and five subunits (a, d, c, c' and c") make up the V0 domain. Like F-ATPase, V-ATPase most likely operates through a rotary mechanism. The V-ATPase V1 B subunit exists as two isoforms. In the inner ear, the V-ATPase B1 isoform functions in proton secretion and is required to maintain proper endolymph pH and normal auditory function. The gene encoding the human V-ATPase B1 isoform maps to chromosome 2cen-q13. Mutations in this gene cause distal renal tubular acidosis associated with sensorineural deafness. The V-ATPase B2 isoform is expressed in kidney and is the only B isoform expressed in osteoclasts. The gene encoding the human V-ATPase B2 isoform maps to chromosome 8p22-p21.

Synonyms: ATP6B, ATP6V1 B, ATP6V1B, ATP6V1B, ATPase H+ transporting lysosomal 56/58 kDa V1 subunit B, ATPase, H+ transporting, Endomembrane proton pump 58 kDa subunit, H+ transporting two sector ATPase, HO 57, HO57, V type proton ATPase subunit B, V-type proton ATPase subunit B, Vacuolar H+ ATPase 56,000 subunit, Vacuolar H+ ATPase 56000 subunit, Vacuolar proton pump subunit B,

Gen-ID 526
Pathways Transition Metal Ion Homeostasis, Proton Transport
Applikations-hinweise IF(IHC-P) 1:50-200
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung 4 °C
Informationen zur Lagerung Store at 4°C
Haltbarkeit 12 months
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