Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

Cofilin Antikörper (pSer24) (Cy5)

Dieses Anti-Cofilin-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von Cofilin in IF (cc) und IF (p). Geeignet für Ratte.
Produktnummer ABIN1704204

Kurzübersicht für Cofilin Antikörper (pSer24) (Cy5) (ABIN1704204)

Target

Alle Cofilin (CFL1) Antikörper anzeigen
Cofilin (CFL1) (Cofilin 1 (CFL1))

Reaktivität

  • 147
  • 96
  • 92
  • 7
  • 5
  • 5
  • 4
  • 2
  • 1
  • 1
  • 1
Ratte

Wirt

  • 141
  • 22
  • 2
  • 1
Kaninchen

Klonalität

  • 141
  • 24
Polyklonal

Konjugat

  • 89
  • 10
  • 10
  • 7
  • 6
  • 5
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser Cofilin Antikörper ist konjugiert mit Cy5

Applikation

  • 89
  • 64
  • 61
  • 44
  • 40
  • 40
  • 36
  • 35
  • 24
  • 22
  • 13
  • 7
  • 3
  • 3
  • 3
  • 2
  • 2
Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • Bindungsspezifität

    • 18
    • 17
    • 16
    • 14
    • 11
    • 9
    • 8
    • 7
    • 7
    • 7
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer24

    Kreuzreaktivität

    Ratte

    Homologie

    Human,Mouse,Dog,Cow,Pig,Chicken,Guinea Pig

    Aufreinigung

    Purified by Protein A.

    Immunogen

    KLH conjugated synthetic phosphopeptide derived from human CFL1/CFL2 around the phosphorylation site of Ser24

    Isotyp

    IgG
  • Applikationshinweise

    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 μg/μL

    Buffer

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    Konservierungsmittel

    ProClin

    Vorsichtsmaßnahmen

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    Haltbarkeit

    12 months
  • Target

    Cofilin (CFL1) (Cofilin 1 (CFL1))

    Andere Bezeichnung

    Cofilin

    Hintergrund

    Synonyms: Cofilin/CFL1 Ser24, 18 kDa phosphoprotein, CFL 1, CFL, CFL1, Cofilin 1, Cofilin 1 non muscle, Cofilin non muscle isoform, p18, COF1_HUMAN.

    Background: The protein encoded by this gene can polymerize and depolymerize F-actin and G-actin in a pH -dependent manner. Increased phosphorylation of this protein by LIM kinase aids in Rho-induced reorganization of the actin cytoskeleton. Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH -dependent manner. It is involved in the translocation of actin-cofilin complex from cytoplasm to nucleus.

    Gen-ID

    1072

    Pathways

    Regulation of Cell Size, Tube Formation, Protein targeting to Nucleus, CXCR4-mediated Signaling Events
Sie sind hier:
Chat with us!