alpha Adducin Antikörper (Adducin 1 (Alpha)) (pSer436) (Cy5)

Details for Product anti-ADD1 Antibody No. ABIN1704199
Antigen
  • ADDA
  • AI256389
  • alpha-adducin
  • bZ1H20.1
  • cb787
  • zgc:158352
  • add2
  • adda
  • add1-a
  • ADD1
  • adducin 1
  • adducin 1 (alpha)
  • adducin 1 S homeolog
  • ADD1
  • Add1
  • add1
  • add1.S
Epitop
pSer436
40
14
10
8
7
5
5
4
3
3
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
Reaktivität
Human, Maus, Ratte (Rattus)
182
139
129
10
7
4
4
3
3
2
2
2
1
1
Wirt
Kaninchen
179
6
Klonalität
Polyklonal
Konjugat
Dieser alpha Adducin Antikörper ist konjugiert mit Cy5
4
4
4
4
4
4
3
2
2
2
2
2
2
2
1
Applikation
Immunofluorescence (Paraffin-embedded Sections) (IF (p))
124
100
59
52
40
27
22
14
13
3
1
1
Optionen
Immunogen KLH conjugated synthetic phosphopeptide derived from human alpha Adducin around the phosphorylation site of Ser436
Isotyp IgG
Reinigung Purified by Protein A.
Plasmids, Primers & others Plasmide, Primers & weitere alpha Adducin products on genomics-online (e.g. as negative or positive controls)
Antigen
Andere Bezeichnung alpha Adducin (ADD1 Antibody Abstract)
Hintergrund

Adducins are a family of cytoskeleton proteins encoded by three genes (Alpha, Beta, Gamma). Adducin is a protein associated with the inner leaflet of the plasma membrane and is one of the proteins localized at the spectrin-actin junction of the membrane skeleton. The cortical actin cytoskeletal network is lost during apoptosis and Adducins are central in the cortical actin network organization. Adducin Alpha is a cytoskeletal protein involved with sodium-pump activity in the renal tubule and is associated with hypertension. The expression of Adducin Alpha and Adducin Gamma is ubiquitous in contrast to the restricted expression of Adducin Beta. Adducin Beta is expressed at high levels in brain and hematopoietic tissues, such as bone marrow, in humans, and in spleen in mice.

Synonyms: alpha Adducinphospho S436, alpha Adducinphospho Ser436, p-alpha AdducinS436, p-alpha AdducinSer436, ADD 1, ADD A, ADD1, ADD1 protein, ADDA, ADDA_HUMAN, Adducin 1 alpha, Adducin 1 alpha, Alpha adducin, Alpha-adducin, Erythrocyte adducin alpha subunit, Erythrocyte hosphor subunit alpha, Erythrocyte adducin subunit alpha.

Gen-ID 118
Pathways Negative Regulation of Hormone Secretion, Regulation of Actin Filament Polymerization, Regulation of Lipid Metabolism by PPARalpha, ER-Nucleus Signaling
Applikations-hinweise IF(IHC-P) 1:50-200
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Lagerung 4 °C
Informationen zur Lagerung Store at 4°C
Haltbarkeit 12 months
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